H3K27 modifications define segmental regulatory domains in the Drosophila bithorax complex

H3K27 modifications define segmental regulatory domains in the Drosophila bithorax complex

The bithorax complex (BX-C) in Drosophila melanogaster is a cluster of homeotic genes that determine body segment identity. Expression of these genes is governed by cis-regulatory domains, one for each parasegment. Stable repression of these domains depends on Polycomb Group (PcG) functions, which i...

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Bibliographic Details
Main Authors: Sarah K Bowman, Aimee M Deaton, Heber Domingues, Peggy I Wang, Ruslan I Sadreyev, Robert E Kingston, Welcome Bender
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-07-01
Series:eLife
Subjects:
chromatin
Polycomb
bithorax complex
CTCF
Online Access:https://elifesciences.org/articles/02833

Internet

https://elifesciences.org/articles/02833

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