A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean
We aimed to study time trends and levels of mean total cholesterol and lipid fractions, and dyslipidaemias prevalence in Latin America and the Caribbean (LAC). Systematic-review and meta-analysis of population-based studies in which lipid (total cholesterol [TC; 86 studies; 168,553 people], HDL-Chol...
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eLife Sciences Publications Ltd
2020-08-01
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Online Access: | https://elifesciences.org/articles/57980 |
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author | Rodrigo M Carrillo-Larco C Joel Benites-Moya Cecilia Anza-Ramirez Leonardo Albitres-Flores Diana Sánchez-Velazco Niels Pacheco-Barrios Antonio Bernabe-Ortiz |
author_facet | Rodrigo M Carrillo-Larco C Joel Benites-Moya Cecilia Anza-Ramirez Leonardo Albitres-Flores Diana Sánchez-Velazco Niels Pacheco-Barrios Antonio Bernabe-Ortiz |
author_sort | Rodrigo M Carrillo-Larco |
collection | DOAJ |
description | We aimed to study time trends and levels of mean total cholesterol and lipid fractions, and dyslipidaemias prevalence in Latin America and the Caribbean (LAC). Systematic-review and meta-analysis of population-based studies in which lipid (total cholesterol [TC; 86 studies; 168,553 people], HDL-Cholesterol [HDL-C; 84 studies; 121,282 people], LDL-Cholesterol [LDL-C; 61 studies; 86,854 people], and triglycerides [TG; 84 studies; 121,009 people]) levels and prevalences were laboratory-based. We used Scopus, LILACS, Embase, Medline and Global Health; studies were from 1964 to 2016. Pooled means and prevalences were estimated for lipid biomarkers from ≥2005. The pooled means (mg/dl) were 193 for TC, 120 for LDL-C, 47 for HDL-C, and 139 for TG; no strong trends. The pooled prevalence estimates were 21% for high TC, 20% for high LDL-C, 48% for low HDL-C, and 21% for high TG; no strong trends. These results may help strengthen programs for dyslipidaemias prevention/management in LAC. |
first_indexed | 2024-04-11T09:03:54Z |
format | Article |
id | doaj.art-8474289f13ad4adb9a3ac6121f7b7109 |
institution | Directory Open Access Journal |
issn | 2050-084X |
language | English |
last_indexed | 2024-04-11T09:03:54Z |
publishDate | 2020-08-01 |
publisher | eLife Sciences Publications Ltd |
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series | eLife |
spelling | doaj.art-8474289f13ad4adb9a3ac6121f7b71092022-12-22T04:32:42ZengeLife Sciences Publications LtdeLife2050-084X2020-08-01910.7554/eLife.57980A systematic review of population-based studies on lipid profiles in Latin America and the CaribbeanRodrigo M Carrillo-Larco0https://orcid.org/0000-0002-2090-1856C Joel Benites-Moya1Cecilia Anza-Ramirez2https://orcid.org/0000-0001-7364-8252Leonardo Albitres-Flores3https://orcid.org/0000-0002-0077-3615Diana Sánchez-Velazco4Niels Pacheco-Barrios5Antonio Bernabe-Ortiz6https://orcid.org/0000-0002-6834-1376Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom; CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru; Universidad Católica Los Ángeles de Chimbote, Instituto de Investigación, Chimbote, PeruCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, PeruCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, PeruCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru; Facultad de Medicina de la Universidad Nacional de Trujillo, Trujillo, Peru; Sociedad Científica de Estudiantes de Medicina de la Universidad Nacional de Trujillo-SOCEMUNT, Trujillo, PeruCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, PeruCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, PeruCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru; Universidad Científica del Sur, Lima, PeruWe aimed to study time trends and levels of mean total cholesterol and lipid fractions, and dyslipidaemias prevalence in Latin America and the Caribbean (LAC). Systematic-review and meta-analysis of population-based studies in which lipid (total cholesterol [TC; 86 studies; 168,553 people], HDL-Cholesterol [HDL-C; 84 studies; 121,282 people], LDL-Cholesterol [LDL-C; 61 studies; 86,854 people], and triglycerides [TG; 84 studies; 121,009 people]) levels and prevalences were laboratory-based. We used Scopus, LILACS, Embase, Medline and Global Health; studies were from 1964 to 2016. Pooled means and prevalences were estimated for lipid biomarkers from ≥2005. The pooled means (mg/dl) were 193 for TC, 120 for LDL-C, 47 for HDL-C, and 139 for TG; no strong trends. The pooled prevalence estimates were 21% for high TC, 20% for high LDL-C, 48% for low HDL-C, and 21% for high TG; no strong trends. These results may help strengthen programs for dyslipidaemias prevention/management in LAC.https://elifesciences.org/articles/57980cholesterolcardiovascularrisk factor |
spellingShingle | Rodrigo M Carrillo-Larco C Joel Benites-Moya Cecilia Anza-Ramirez Leonardo Albitres-Flores Diana Sánchez-Velazco Niels Pacheco-Barrios Antonio Bernabe-Ortiz A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean eLife cholesterol cardiovascular risk factor |
title | A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean |
title_full | A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean |
title_fullStr | A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean |
title_full_unstemmed | A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean |
title_short | A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean |
title_sort | systematic review of population based studies on lipid profiles in latin america and the caribbean |
topic | cholesterol cardiovascular risk factor |
url | https://elifesciences.org/articles/57980 |
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