A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean

We aimed to study time trends and levels of mean total cholesterol and lipid fractions, and dyslipidaemias prevalence in Latin America and the Caribbean (LAC). Systematic-review and meta-analysis of population-based studies in which lipid (total cholesterol [TC; 86 studies; 168,553 people], HDL-Chol...

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Main Authors: Rodrigo M Carrillo-Larco, C Joel Benites-Moya, Cecilia Anza-Ramirez, Leonardo Albitres-Flores, Diana Sánchez-Velazco, Niels Pacheco-Barrios, Antonio Bernabe-Ortiz
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/57980
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author Rodrigo M Carrillo-Larco
C Joel Benites-Moya
Cecilia Anza-Ramirez
Leonardo Albitres-Flores
Diana Sánchez-Velazco
Niels Pacheco-Barrios
Antonio Bernabe-Ortiz
author_facet Rodrigo M Carrillo-Larco
C Joel Benites-Moya
Cecilia Anza-Ramirez
Leonardo Albitres-Flores
Diana Sánchez-Velazco
Niels Pacheco-Barrios
Antonio Bernabe-Ortiz
author_sort Rodrigo M Carrillo-Larco
collection DOAJ
description We aimed to study time trends and levels of mean total cholesterol and lipid fractions, and dyslipidaemias prevalence in Latin America and the Caribbean (LAC). Systematic-review and meta-analysis of population-based studies in which lipid (total cholesterol [TC; 86 studies; 168,553 people], HDL-Cholesterol [HDL-C; 84 studies; 121,282 people], LDL-Cholesterol [LDL-C; 61 studies; 86,854 people], and triglycerides [TG; 84 studies; 121,009 people]) levels and prevalences were laboratory-based. We used Scopus, LILACS, Embase, Medline and Global Health; studies were from 1964 to 2016. Pooled means and prevalences were estimated for lipid biomarkers from ≥2005. The pooled means (mg/dl) were 193 for TC, 120 for LDL-C, 47 for HDL-C, and 139 for TG; no strong trends. The pooled prevalence estimates were 21% for high TC, 20% for high LDL-C, 48% for low HDL-C, and 21% for high TG; no strong trends. These results may help strengthen programs for dyslipidaemias prevention/management in LAC.
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spelling doaj.art-8474289f13ad4adb9a3ac6121f7b71092022-12-22T04:32:42ZengeLife Sciences Publications LtdeLife2050-084X2020-08-01910.7554/eLife.57980A systematic review of population-based studies on lipid profiles in Latin America and the CaribbeanRodrigo M Carrillo-Larco0https://orcid.org/0000-0002-2090-1856C Joel Benites-Moya1Cecilia Anza-Ramirez2https://orcid.org/0000-0001-7364-8252Leonardo Albitres-Flores3https://orcid.org/0000-0002-0077-3615Diana Sánchez-Velazco4Niels Pacheco-Barrios5Antonio Bernabe-Ortiz6https://orcid.org/0000-0002-6834-1376Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom; CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru; Universidad Católica Los Ángeles de Chimbote, Instituto de Investigación, Chimbote, PeruCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, PeruCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, PeruCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru; Facultad de Medicina de la Universidad Nacional de Trujillo, Trujillo, Peru; Sociedad Científica de Estudiantes de Medicina de la Universidad Nacional de Trujillo-SOCEMUNT, Trujillo, PeruCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, PeruCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, PeruCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru; Universidad Científica del Sur, Lima, PeruWe aimed to study time trends and levels of mean total cholesterol and lipid fractions, and dyslipidaemias prevalence in Latin America and the Caribbean (LAC). Systematic-review and meta-analysis of population-based studies in which lipid (total cholesterol [TC; 86 studies; 168,553 people], HDL-Cholesterol [HDL-C; 84 studies; 121,282 people], LDL-Cholesterol [LDL-C; 61 studies; 86,854 people], and triglycerides [TG; 84 studies; 121,009 people]) levels and prevalences were laboratory-based. We used Scopus, LILACS, Embase, Medline and Global Health; studies were from 1964 to 2016. Pooled means and prevalences were estimated for lipid biomarkers from ≥2005. The pooled means (mg/dl) were 193 for TC, 120 for LDL-C, 47 for HDL-C, and 139 for TG; no strong trends. The pooled prevalence estimates were 21% for high TC, 20% for high LDL-C, 48% for low HDL-C, and 21% for high TG; no strong trends. These results may help strengthen programs for dyslipidaemias prevention/management in LAC.https://elifesciences.org/articles/57980cholesterolcardiovascularrisk factor
spellingShingle Rodrigo M Carrillo-Larco
C Joel Benites-Moya
Cecilia Anza-Ramirez
Leonardo Albitres-Flores
Diana Sánchez-Velazco
Niels Pacheco-Barrios
Antonio Bernabe-Ortiz
A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean
eLife
cholesterol
cardiovascular
risk factor
title A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean
title_full A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean
title_fullStr A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean
title_full_unstemmed A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean
title_short A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean
title_sort systematic review of population based studies on lipid profiles in latin america and the caribbean
topic cholesterol
cardiovascular
risk factor
url https://elifesciences.org/articles/57980
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