Effect of Ramadan fasting on alanine transferase (ALT) in nonalcoholic fatty liver disease (NAFLD)
Background: The effects of Ramadan fasting on NAFLD are unknown and there are very limited studies have done in this area. Some nutritional and behavioral changes of fasting people in Ramadan can affect NAFLD. These include nutrition with high fat and calories, altering in weight and sleep and low p...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2017-09-01
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| Series: | Journal of Fasting and Health |
| Subjects: | |
| Online Access: | http://jfh.mums.ac.ir/article_9128_d3711b108713d58fb9beae00afb86c39.pdf |
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| author | Hojjatolah Rahimi Mohammad Emad Habibi Ali Gharavinia Mohammad hasan Emami Abdolmahdi Baghaei Najmeh Tavakol |
| author_facet | Hojjatolah Rahimi Mohammad Emad Habibi Ali Gharavinia Mohammad hasan Emami Abdolmahdi Baghaei Najmeh Tavakol |
| author_sort | Hojjatolah Rahimi |
| collection | DOAJ |
| description | Background: The effects of Ramadan fasting on NAFLD are unknown and there are very limited studies have done in this area. Some nutritional and behavioral changes of fasting people in Ramadan can affect NAFLD. These include nutrition with high fat and calories, altering in weight and sleep and low physical activity. We decided to evaluate the effects of these changes on one of the important indicators of deterioration of NAFLD, ALT.Methods: Sixty patients with fatty liver disease performed two consecutive ALT exams before and after Ramadan month of whom finally 34 were fasting and 26 nonfasting. After collecting data they were divided in two groups of fasting and nonfasting and compared using SPSS software.Results: Mean ALT change from before to after Ramadan was higher and positive in fasting (+7.38±8.47 IU/L) compared to nonfastng patients that was negative (-0.12±10.15 IU/L) (P=0.002) and this change was mainly in patients who had fasted 21-30 days.Conclusion: Ramadan fasting may increase ALT. It is needed to perform more studies in patients with NAFLD during Ramadan fasting with larger sample size and in various conditions especially weight loss with patients’ education for observing dietary regimen. |
| first_indexed | 2024-12-11T18:03:12Z |
| format | Article |
| id | doaj.art-8479b4a363b14d059976260d2c10213b |
| institution | Directory Open Access Journal |
| issn | 2345-2587 2345-2587 |
| language | English |
| last_indexed | 2024-12-11T18:03:12Z |
| publishDate | 2017-09-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Journal of Fasting and Health |
| spelling | doaj.art-8479b4a363b14d059976260d2c10213b2022-12-22T00:55:50ZengMashhad University of Medical SciencesJournal of Fasting and Health2345-25872345-25872017-09-015310711210.22038/jfh.2017.24588.10899128Effect of Ramadan fasting on alanine transferase (ALT) in nonalcoholic fatty liver disease (NAFLD)Hojjatolah Rahimi0Mohammad Emad Habibi1Ali Gharavinia2Mohammad hasan Emami3Abdolmahdi Baghaei4Najmeh Tavakol5Gastrointestinal and Hepatobiliary Diseases Research Center, Poursina Hakim Research Institute for Health Care Development, Isfahan, Iran.Gastrointestinal and Hepatobiliary Diseases Research Center, Poursina Hakim Research Institute for Health Care Development, Isfahan, Iran.Gastrointestinal and Hepatobiliary Diseases Research Center, Poursina Hakim Research Institute for Health Care Development, Isfahan, Iran.Gastrointestinal and Hepatobiliary Diseases Research Center, Poursina Hakim Research Institute for Health Care Development, Isfahan, Iran.Gastrointestinal and Hepatobiliary Diseases Research Center, Poursina Hakim Research Institute for Health Care Development, Isfahan, Iran.Gastrointestinal and Hepatobiliary Diseases Research Center, Poursina Hakim Research Institute for Health Care Development, Isfahan, Iran.Background: The effects of Ramadan fasting on NAFLD are unknown and there are very limited studies have done in this area. Some nutritional and behavioral changes of fasting people in Ramadan can affect NAFLD. These include nutrition with high fat and calories, altering in weight and sleep and low physical activity. We decided to evaluate the effects of these changes on one of the important indicators of deterioration of NAFLD, ALT.Methods: Sixty patients with fatty liver disease performed two consecutive ALT exams before and after Ramadan month of whom finally 34 were fasting and 26 nonfasting. After collecting data they were divided in two groups of fasting and nonfasting and compared using SPSS software.Results: Mean ALT change from before to after Ramadan was higher and positive in fasting (+7.38±8.47 IU/L) compared to nonfastng patients that was negative (-0.12±10.15 IU/L) (P=0.002) and this change was mainly in patients who had fasted 21-30 days.Conclusion: Ramadan fasting may increase ALT. It is needed to perform more studies in patients with NAFLD during Ramadan fasting with larger sample size and in various conditions especially weight loss with patients’ education for observing dietary regimen.http://jfh.mums.ac.ir/article_9128_d3711b108713d58fb9beae00afb86c39.pdfALTfastingRamadan |
| spellingShingle | Hojjatolah Rahimi Mohammad Emad Habibi Ali Gharavinia Mohammad hasan Emami Abdolmahdi Baghaei Najmeh Tavakol Effect of Ramadan fasting on alanine transferase (ALT) in nonalcoholic fatty liver disease (NAFLD) Journal of Fasting and Health ALT fasting Ramadan |
| title | Effect of Ramadan fasting on alanine transferase (ALT) in nonalcoholic fatty liver disease (NAFLD) |
| title_full | Effect of Ramadan fasting on alanine transferase (ALT) in nonalcoholic fatty liver disease (NAFLD) |
| title_fullStr | Effect of Ramadan fasting on alanine transferase (ALT) in nonalcoholic fatty liver disease (NAFLD) |
| title_full_unstemmed | Effect of Ramadan fasting on alanine transferase (ALT) in nonalcoholic fatty liver disease (NAFLD) |
| title_short | Effect of Ramadan fasting on alanine transferase (ALT) in nonalcoholic fatty liver disease (NAFLD) |
| title_sort | effect of ramadan fasting on alanine transferase alt in nonalcoholic fatty liver disease nafld |
| topic | ALT fasting Ramadan |
| url | http://jfh.mums.ac.ir/article_9128_d3711b108713d58fb9beae00afb86c39.pdf |
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