3367 A Mouse Model of APOE Genotype in Chemotherapy Related Cognitive Impairment

OBJECTIVES/SPECIFIC AIMS: Chemotherapy-related cognitive impairment (CRCI) affects 15-35% of breast cancer survivors and constitutes a significant challenge for survivor quality of life. Among older breast cancer survivors who received chemotherapy treatment, carriers of at least one ɛ4 allele of th...

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Bibliographic Details
Main Authors: Tamar Demby, G. William Rebeck, Christopher Albanese, Olga C. Rodriguez, Yichien Lee, Jeanne Mandelblatt
Format: Article
Language:English
Published: Cambridge University Press 2019-03-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866119000062/type/journal_article