General concepts in biostatistics and clinical epidemiology: observational studies with cohort design

Cohort studies evaluate the relationship between an exposure and the occurrence or lack thereof an outcome of interest, initiating from the exposure. This methodological design has been widely used in some areas of medicine, such as the study of cardiovascular risk factors or the effects of ionizing...

Full description

Bibliographic Details
Main Authors: Gabriel Lazcano, Cristian Papuzinski, Eva Madrid, Marcelo Arancibia
Format: Article
Language:English
Published: Medwave Estudios Limitada 2019-12-01
Series:Medwave
Subjects:
Online Access:https://www.medwave.cl/link.cgi/Medwave/Revisiones/MetodInvestReport/7748.act
_version_ 1819017254009831424
author Gabriel Lazcano
Cristian Papuzinski
Eva Madrid
Marcelo Arancibia
author_facet Gabriel Lazcano
Cristian Papuzinski
Eva Madrid
Marcelo Arancibia
author_sort Gabriel Lazcano
collection DOAJ
description Cohort studies evaluate the relationship between an exposure and the occurrence or lack thereof an outcome of interest, initiating from the exposure. This methodological design has been widely used in some areas of medicine, such as the study of cardiovascular risk factors or the effects of ionizing radiation in humans. It exhibits attractive properties due to its adaptability to various contexts, especially in the study of low occurrence exposures. This is the fourth of a methodological series on general concepts in biostatistics and clinical epidemiology developed by the Chair of Scientific Research Methodology at the School of Medicine, University of Valparaíso, Chile. It covers general theoretical concepts about cohort studies, considering historical aspects, elements related to the construction of a study using this design, variations and derived designs, as well as potential biases that the researcher might face.
first_indexed 2024-12-21T03:00:36Z
format Article
id doaj.art-84823e09b91d42d694048c68953b64ee
institution Directory Open Access Journal
issn 0717-6384
0717-6384
language English
last_indexed 2024-12-21T03:00:36Z
publishDate 2019-12-01
publisher Medwave Estudios Limitada
record_format Article
series Medwave
spelling doaj.art-84823e09b91d42d694048c68953b64ee2022-12-21T19:18:12ZengMedwave Estudios LimitadaMedwave0717-63840717-63842019-12-011911e7748e774810.5867/medwave.2019.11.7748General concepts in biostatistics and clinical epidemiology: observational studies with cohort designGabriel Lazcano0Cristian Papuzinski1Eva Madrid2Marcelo Arancibia3Cátedra de Metodología de la Investigación Científica, Escuela de Medicina, Universidad de Valparaíso, Viña del Mar, ChileCátedra de Metodología de la Investigación Científica, Escuela de Medicina, Universidad de Valparaíso, Viña del Mar, Chile; Centro Interdisciplinario de Estudios en Salud (CIESAL), Universidad de Valparaíso, Valparaíso, ChileCátedra de Metodología de la Investigación Científica, Escuela de Medicina, Universidad de Valparaíso, Viña del Mar, Chile; Centro Interdisciplinario de Estudios en Salud (CIESAL), Universidad de Valparaíso, Valparaíso, ChileCátedra de Metodología de la Investigación Científica, Escuela de Medicina, Universidad de Valparaíso, Viña del Mar, Chile; Centro Interdisciplinario de Estudios en Salud (CIESAL), Universidad de Valparaíso, Valparaíso, ChileCohort studies evaluate the relationship between an exposure and the occurrence or lack thereof an outcome of interest, initiating from the exposure. This methodological design has been widely used in some areas of medicine, such as the study of cardiovascular risk factors or the effects of ionizing radiation in humans. It exhibits attractive properties due to its adaptability to various contexts, especially in the study of low occurrence exposures. This is the fourth of a methodological series on general concepts in biostatistics and clinical epidemiology developed by the Chair of Scientific Research Methodology at the School of Medicine, University of Valparaíso, Chile. It covers general theoretical concepts about cohort studies, considering historical aspects, elements related to the construction of a study using this design, variations and derived designs, as well as potential biases that the researcher might face.https://www.medwave.cl/link.cgi/Medwave/Revisiones/MetodInvestReport/7748.actobservational studycohort studiesrelative riskincidencebiasepidemiologybiostatistics
spellingShingle Gabriel Lazcano
Cristian Papuzinski
Eva Madrid
Marcelo Arancibia
General concepts in biostatistics and clinical epidemiology: observational studies with cohort design
Medwave
observational study
cohort studies
relative risk
incidence
bias
epidemiology
biostatistics
title General concepts in biostatistics and clinical epidemiology: observational studies with cohort design
title_full General concepts in biostatistics and clinical epidemiology: observational studies with cohort design
title_fullStr General concepts in biostatistics and clinical epidemiology: observational studies with cohort design
title_full_unstemmed General concepts in biostatistics and clinical epidemiology: observational studies with cohort design
title_short General concepts in biostatistics and clinical epidemiology: observational studies with cohort design
title_sort general concepts in biostatistics and clinical epidemiology observational studies with cohort design
topic observational study
cohort studies
relative risk
incidence
bias
epidemiology
biostatistics
url https://www.medwave.cl/link.cgi/Medwave/Revisiones/MetodInvestReport/7748.act
work_keys_str_mv AT gabriellazcano generalconceptsinbiostatisticsandclinicalepidemiologyobservationalstudieswithcohortdesign
AT cristianpapuzinski generalconceptsinbiostatisticsandclinicalepidemiologyobservationalstudieswithcohortdesign
AT evamadrid generalconceptsinbiostatisticsandclinicalepidemiologyobservationalstudieswithcohortdesign
AT marceloarancibia generalconceptsinbiostatisticsandclinicalepidemiologyobservationalstudieswithcohortdesign