Mesenteric panniculitis mimicking early recurrence at end-of-treatment evaluation in malignant lymphoma: Differentiation by active surveillance with F-18 FDG PET/CT imaging
Mesenteric panniculitis is a relatively rare fibro-inflammatory condition of the mesentery. In acute phase, it demonstrates avid uptake on Fluorine-18 FDG PET/CT (PET/CT). Thorough assessment is needed to differentiate from viable or recurrent disease in patients with malignant lymphoma because it m...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-07-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043320301680 |
| _version_ | 1818020155558461440 |
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| author | Mitsutomi Ishiyama, MD Manuela Matesan, MD, PhD |
| author_facet | Mitsutomi Ishiyama, MD Manuela Matesan, MD, PhD |
| author_sort | Mitsutomi Ishiyama, MD |
| collection | DOAJ |
| description | Mesenteric panniculitis is a relatively rare fibro-inflammatory condition of the mesentery. In acute phase, it demonstrates avid uptake on Fluorine-18 FDG PET/CT (PET/CT). Thorough assessment is needed to differentiate from viable or recurrent disease in patients with malignant lymphoma because it mimics active lymphomatous disease on PET/CT. In this article, 3 illustrative cases of malignant lymphoma are presented. PET/CT demonstrated new FDG-avid mesenteric lesions at the end-of-treatment evaluation while the original disease showed significant response. Early recurrence was initially suspected, but together with clinical course and findings, active surveillance was opted. Sequential follow-up PET/CTs showed various patterns of metabolic activity over time; it can persist for months or more, or metabolic activity can fluctuate over time. Eventually benignity was confirmed in these cases. These cases underscore the importance of interpretation with clinical context and awareness of chronological metabolic changes of mesenteric panniculitis to determine proper management. |
| first_indexed | 2024-04-14T08:02:10Z |
| format | Article |
| id | doaj.art-8482a98dd7d247859affddf8afd706bc |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-04-14T08:02:10Z |
| publishDate | 2020-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-8482a98dd7d247859affddf8afd706bc2022-12-22T02:04:52ZengElsevierRadiology Case Reports1930-04332020-07-0115710061010Mesenteric panniculitis mimicking early recurrence at end-of-treatment evaluation in malignant lymphoma: Differentiation by active surveillance with F-18 FDG PET/CT imagingMitsutomi Ishiyama, MD0Manuela Matesan, MD, PhD1Department of Radiology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, 3-8-31, Ariake, Koto, Tokyo 135-8550, Japan; Corresponding author.Department of Radiology, University of Washington, Seattle, WA 98195, USAMesenteric panniculitis is a relatively rare fibro-inflammatory condition of the mesentery. In acute phase, it demonstrates avid uptake on Fluorine-18 FDG PET/CT (PET/CT). Thorough assessment is needed to differentiate from viable or recurrent disease in patients with malignant lymphoma because it mimics active lymphomatous disease on PET/CT. In this article, 3 illustrative cases of malignant lymphoma are presented. PET/CT demonstrated new FDG-avid mesenteric lesions at the end-of-treatment evaluation while the original disease showed significant response. Early recurrence was initially suspected, but together with clinical course and findings, active surveillance was opted. Sequential follow-up PET/CTs showed various patterns of metabolic activity over time; it can persist for months or more, or metabolic activity can fluctuate over time. Eventually benignity was confirmed in these cases. These cases underscore the importance of interpretation with clinical context and awareness of chronological metabolic changes of mesenteric panniculitis to determine proper management.http://www.sciencedirect.com/science/article/pii/S1930043320301680Mesenteric panniculitisFDG PET/CTMalignant lymphomaEarly recurrence |
| spellingShingle | Mitsutomi Ishiyama, MD Manuela Matesan, MD, PhD Mesenteric panniculitis mimicking early recurrence at end-of-treatment evaluation in malignant lymphoma: Differentiation by active surveillance with F-18 FDG PET/CT imaging Radiology Case Reports Mesenteric panniculitis FDG PET/CT Malignant lymphoma Early recurrence |
| title | Mesenteric panniculitis mimicking early recurrence at end-of-treatment evaluation in malignant lymphoma: Differentiation by active surveillance with F-18 FDG PET/CT imaging |
| title_full | Mesenteric panniculitis mimicking early recurrence at end-of-treatment evaluation in malignant lymphoma: Differentiation by active surveillance with F-18 FDG PET/CT imaging |
| title_fullStr | Mesenteric panniculitis mimicking early recurrence at end-of-treatment evaluation in malignant lymphoma: Differentiation by active surveillance with F-18 FDG PET/CT imaging |
| title_full_unstemmed | Mesenteric panniculitis mimicking early recurrence at end-of-treatment evaluation in malignant lymphoma: Differentiation by active surveillance with F-18 FDG PET/CT imaging |
| title_short | Mesenteric panniculitis mimicking early recurrence at end-of-treatment evaluation in malignant lymphoma: Differentiation by active surveillance with F-18 FDG PET/CT imaging |
| title_sort | mesenteric panniculitis mimicking early recurrence at end of treatment evaluation in malignant lymphoma differentiation by active surveillance with f 18 fdg pet ct imaging |
| topic | Mesenteric panniculitis FDG PET/CT Malignant lymphoma Early recurrence |
| url | http://www.sciencedirect.com/science/article/pii/S1930043320301680 |
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