Pancreatic Tuberculosis: Current Update on Clinical Manifestation and Diagnostic Modalities

Pancreatic tuberculosis is a very rare disease in either immunocompetent or immunocompromised hosts.The incidence of pancreatic tuberculosis was reported to be less than 4.7% in an autopsy series on tuberculosis patients in 1944 and 2% in another autopsy series in 1966.Despite that, in recent times,...

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Main Authors: Samudra Andi Yusuf, Hasan Maulahela, Anjar Raraswati, Maureen Irawati Koesnadi
Format: Article
Language:English
Published: Interna Publishing 2022-01-01
Series:The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Subjects:
Online Access:https://www.ina-jghe.com/index.php/jghe/article/view/806
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author Samudra Andi Yusuf
Hasan Maulahela
Anjar Raraswati
Maureen Irawati Koesnadi
author_facet Samudra Andi Yusuf
Hasan Maulahela
Anjar Raraswati
Maureen Irawati Koesnadi
author_sort Samudra Andi Yusuf
collection DOAJ
description Pancreatic tuberculosis is a very rare disease in either immunocompetent or immunocompromised hosts.The incidence of pancreatic tuberculosis was reported to be less than 4.7% in an autopsy series on tuberculosis patients in 1944 and 2% in another autopsy series in 1966.Despite that, in recent times, an increase in the number of reports of pancreatic TB has been noted.This condition is possibly caused by an improvement in diagnostic imaging tools, the development of different techniques that make obtaining specimens from the pancreas possible, and an increase in HIV prevalence worldwide. Therefore, this review article discusses the current update in the clinical manifestations and diagnostic modalities of pancreatic tuberculosis.Pancreatic tuberculosis is a very rare condition with a various range of non-specific clinical presentation and image features overlapping with those seen in pancreatic neoplasia. A combination of diagnostic modalities should be done to establish a diagnosis of pancreatic tuberculosis. Currently, direct histopathological examination is the best way of diagnosing tuberculosis. US/CT/EUS-guided biopsy is the recommended diagnostic technique. Most patients with pancreatic tuberculosis respond well to anti-tuberculosis drugs.
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spelling doaj.art-84832893541243be85d4af73f997960d2023-06-06T04:42:34ZengInterna PublishingThe Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy1411-48012302-81812022-01-0122321722510.24871/2232021217-225759Pancreatic Tuberculosis: Current Update on Clinical Manifestation and Diagnostic ModalitiesSamudra Andi Yusuf0Hasan Maulahela1Anjar Raraswati2Maureen Irawati Koesnadi3Abdi Waluyo General Hospital, JakartaDivision of Gastroenterology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia/Dr. Cipto Mangunkusumo General National Hospital, Indonesia, Indonesian Medical Education and Research Institute (IMERI), Cluster of Infectious DiseasesFaculty of Medicine, Universitas Padjajaran, BandungAbdi Waluyo General Hospital, JakartaPancreatic tuberculosis is a very rare disease in either immunocompetent or immunocompromised hosts.The incidence of pancreatic tuberculosis was reported to be less than 4.7% in an autopsy series on tuberculosis patients in 1944 and 2% in another autopsy series in 1966.Despite that, in recent times, an increase in the number of reports of pancreatic TB has been noted.This condition is possibly caused by an improvement in diagnostic imaging tools, the development of different techniques that make obtaining specimens from the pancreas possible, and an increase in HIV prevalence worldwide. Therefore, this review article discusses the current update in the clinical manifestations and diagnostic modalities of pancreatic tuberculosis.Pancreatic tuberculosis is a very rare condition with a various range of non-specific clinical presentation and image features overlapping with those seen in pancreatic neoplasia. A combination of diagnostic modalities should be done to establish a diagnosis of pancreatic tuberculosis. Currently, direct histopathological examination is the best way of diagnosing tuberculosis. US/CT/EUS-guided biopsy is the recommended diagnostic technique. Most patients with pancreatic tuberculosis respond well to anti-tuberculosis drugs.https://www.ina-jghe.com/index.php/jghe/article/view/806pancreatic tuberculosisdiagnosisclinical manifestationusgct scanmripcrhistopathologyeus fna
spellingShingle Samudra Andi Yusuf
Hasan Maulahela
Anjar Raraswati
Maureen Irawati Koesnadi
Pancreatic Tuberculosis: Current Update on Clinical Manifestation and Diagnostic Modalities
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
pancreatic tuberculosis
diagnosis
clinical manifestation
usg
ct scan
mri
pcr
histopathology
eus fna
title Pancreatic Tuberculosis: Current Update on Clinical Manifestation and Diagnostic Modalities
title_full Pancreatic Tuberculosis: Current Update on Clinical Manifestation and Diagnostic Modalities
title_fullStr Pancreatic Tuberculosis: Current Update on Clinical Manifestation and Diagnostic Modalities
title_full_unstemmed Pancreatic Tuberculosis: Current Update on Clinical Manifestation and Diagnostic Modalities
title_short Pancreatic Tuberculosis: Current Update on Clinical Manifestation and Diagnostic Modalities
title_sort pancreatic tuberculosis current update on clinical manifestation and diagnostic modalities
topic pancreatic tuberculosis
diagnosis
clinical manifestation
usg
ct scan
mri
pcr
histopathology
eus fna
url https://www.ina-jghe.com/index.php/jghe/article/view/806
work_keys_str_mv AT samudraandiyusuf pancreatictuberculosiscurrentupdateonclinicalmanifestationanddiagnosticmodalities
AT hasanmaulahela pancreatictuberculosiscurrentupdateonclinicalmanifestationanddiagnosticmodalities
AT anjarraraswati pancreatictuberculosiscurrentupdateonclinicalmanifestationanddiagnosticmodalities
AT maureenirawatikoesnadi pancreatictuberculosiscurrentupdateonclinicalmanifestationanddiagnosticmodalities