[<sup>89</sup>Zr]-Pertuzumab PET Imaging Reveals Paclitaxel Treatment Efficacy Is Positively Correlated with HER2 Expression in Human Breast Cancer Xenograft Mouse Models

[<sup>89</sup>Zr]-Pertuzumab PET Imaging Reveals Paclitaxel Treatment Efficacy Is Positively Correlated with HER2 Expression in Human Breast Cancer Xenograft Mouse Models

Paclitaxel (PTX) treatment efficacy varies in breast cancer, yet the underlying mechanism for variable response remains unclear. This study evaluates whether human epidermal growth factor receptor 2 (HER2) expression level utilizing advanced molecular positron emission tomography (PET) imaging is co...

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Bibliographic Details
Main Authors: Yun Lu, Meng Li, Adriana V. F. Massicano, Patrick N. Song, Ameer Mansur, Katherine A. Heinzman, Benjamin M. Larimer, Suzanne E. Lapi, Anna G. Sorace
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
positron emission tomography
FDG-PET
heterogeneity
HER2+ breast cancer
molecular imaging
Online Access:https://www.mdpi.com/1420-3049/26/6/1568

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