Pharmacological doses of daily ascorbate protect tumours from radiation damage after a single dose of radiation in an intracranial mouse glioma model
Pharmacological ascorbate is currently used as an anti-cancer treatment, potentially in combination with radiation therapy, by integrative medicine practitioners. In the acidic, metal-rich tumour environment, ascorbate acts as a pro-oxidant, with a mode of action similar to that of ionising radiatio...
Main Authors: | Carole eGrasso, Marie-Sophie eFabre, Sarah V Collis, M Leticia Castro, Cameron S Field, Nanette eSchleich, Melanie J McConnell, Patries M Herst |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-12-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00356/full |
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