Sex-stratified RNA-seq analysis reveals traumatic brain injury-induced transcriptional changes in the female hippocampus conducive to dementia

Sex-stratified RNA-seq analysis reveals traumatic brain injury-induced transcriptional changes in the female hippocampus conducive to dementia

IntroductionTraumatic brain injury (TBI), resulting from a violent force that causes functional changes in the brain, is the foremost environmental risk factor for developing dementia. While previous studies have identified specific candidate genes that may instigate worse outcomes following TBI whe...

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Bibliographic Details
Main Authors: Michael R. Fiorini, Allison A. Dilliott, Sali M. K. Farhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Neurology
Subjects:
traumatic brain injury
dementia
RNA sequencing
transcriptome
hippocampus
sex
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.1026448/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2022.1026448/full

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