Pain in IBD Patients: Very Frequent and Frequently Insufficiently Taken into Account.
Pain is a common symptom related to inflammatory bowel disease (IBD). In addition to abdominal pain, pain can also be an extraintestinal manifestation of IBD. Pain treatment is challenging and a substantial part of IBD patients are treated with opioids. Therefore, a better knowledge on pain symptoms...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2016-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4917102?pdf=render |
| _version_ | 1819266420470448128 |
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| author | Jonas Zeitz Melike Ak Séverine Müller-Mottet Sylvie Scharl Luc Biedermann Nicolas Fournier Pascal Frei Valerie Pittet Michael Scharl Michael Fried Gerhard Rogler Stephan Vavricka Swiss IBD Cohort Study Group |
| author_facet | Jonas Zeitz Melike Ak Séverine Müller-Mottet Sylvie Scharl Luc Biedermann Nicolas Fournier Pascal Frei Valerie Pittet Michael Scharl Michael Fried Gerhard Rogler Stephan Vavricka Swiss IBD Cohort Study Group |
| author_sort | Jonas Zeitz |
| collection | DOAJ |
| description | Pain is a common symptom related to inflammatory bowel disease (IBD). In addition to abdominal pain, pain can also be an extraintestinal manifestation of IBD. Pain treatment is challenging and a substantial part of IBD patients are treated with opioids. Therefore, a better knowledge on pain symptoms is crucial for a better therapeutic approach to this clinical problem.Patients of the Swiss IBD Cohort Study (SIBDCS) (n = 2152) received a questionnaire regarding pain intensity, pain localization and impact of pain on daily life and social activities. Furthermore, the questionnaire investigated the use of pain-specific medication.A vast majority of patients (71%) experienced pain during the disease course. For a substantial part of patients (49% in UC and 55% in CD) pain is a longstanding problem (>5 years). Pain in UC was of shorter duration compared to CD (p < 0.01). Abdominal pain (59.5%) and back pain (38.3%) were the main pain localizations. 67% of patients took pain medication; 24% received no pain treatment. The general quality of life was significantly lower in patients suffering of pain compared to those without pain (38 vs. 77; (-100 very bad; 100 very good) p<0.0001).Prevalence of pain is high in patients of the SIBDCS. It is a longstanding problem for the majority of the patients affected. Pain was found to be undertreated in the SIBDCS and was significantly associated with health-related quality of life. Thus, an increased awareness is mandatory to address this frequent complication in the course of IBD. |
| first_indexed | 2024-12-23T21:00:59Z |
| format | Article |
| id | doaj.art-848a1db94f424de58356c95171a3ea42 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-23T21:00:59Z |
| publishDate | 2016-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-848a1db94f424de58356c95171a3ea422022-12-21T17:31:23ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01116e015666610.1371/journal.pone.0156666Pain in IBD Patients: Very Frequent and Frequently Insufficiently Taken into Account.Jonas ZeitzMelike AkSéverine Müller-MottetSylvie ScharlLuc BiedermannNicolas FournierPascal FreiValerie PittetMichael ScharlMichael FriedGerhard RoglerStephan VavrickaSwiss IBD Cohort Study GroupPain is a common symptom related to inflammatory bowel disease (IBD). In addition to abdominal pain, pain can also be an extraintestinal manifestation of IBD. Pain treatment is challenging and a substantial part of IBD patients are treated with opioids. Therefore, a better knowledge on pain symptoms is crucial for a better therapeutic approach to this clinical problem.Patients of the Swiss IBD Cohort Study (SIBDCS) (n = 2152) received a questionnaire regarding pain intensity, pain localization and impact of pain on daily life and social activities. Furthermore, the questionnaire investigated the use of pain-specific medication.A vast majority of patients (71%) experienced pain during the disease course. For a substantial part of patients (49% in UC and 55% in CD) pain is a longstanding problem (>5 years). Pain in UC was of shorter duration compared to CD (p < 0.01). Abdominal pain (59.5%) and back pain (38.3%) were the main pain localizations. 67% of patients took pain medication; 24% received no pain treatment. The general quality of life was significantly lower in patients suffering of pain compared to those without pain (38 vs. 77; (-100 very bad; 100 very good) p<0.0001).Prevalence of pain is high in patients of the SIBDCS. It is a longstanding problem for the majority of the patients affected. Pain was found to be undertreated in the SIBDCS and was significantly associated with health-related quality of life. Thus, an increased awareness is mandatory to address this frequent complication in the course of IBD.http://europepmc.org/articles/PMC4917102?pdf=render |
| spellingShingle | Jonas Zeitz Melike Ak Séverine Müller-Mottet Sylvie Scharl Luc Biedermann Nicolas Fournier Pascal Frei Valerie Pittet Michael Scharl Michael Fried Gerhard Rogler Stephan Vavricka Swiss IBD Cohort Study Group Pain in IBD Patients: Very Frequent and Frequently Insufficiently Taken into Account. PLoS ONE |
| title | Pain in IBD Patients: Very Frequent and Frequently Insufficiently Taken into Account. |
| title_full | Pain in IBD Patients: Very Frequent and Frequently Insufficiently Taken into Account. |
| title_fullStr | Pain in IBD Patients: Very Frequent and Frequently Insufficiently Taken into Account. |
| title_full_unstemmed | Pain in IBD Patients: Very Frequent and Frequently Insufficiently Taken into Account. |
| title_short | Pain in IBD Patients: Very Frequent and Frequently Insufficiently Taken into Account. |
| title_sort | pain in ibd patients very frequent and frequently insufficiently taken into account |
| url | http://europepmc.org/articles/PMC4917102?pdf=render |
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