The ADP-Ribosylating Toxins of <i>Salmonella</i>
A number of pathogenic bacteria utilize toxins to mediate disease in a susceptible host. The foodborne pathogen <i>Salmonella</i> is one of the most important and well-studied bacterial pathogens. Recently, whole genome sequence characterizations revealed the presence of multiple novel A...
| Главные авторы: | , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
MDPI AG
2019-07-01
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| Серии: | Toxins |
| Предметы: | |
| Online-ссылка: | https://www.mdpi.com/2072-6651/11/7/416 |
| _version_ | 1828371492494114816 |
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| author | Rachel A. Cheng Martin Wiedmann |
| author_facet | Rachel A. Cheng Martin Wiedmann |
| author_sort | Rachel A. Cheng |
| collection | DOAJ |
| description | A number of pathogenic bacteria utilize toxins to mediate disease in a susceptible host. The foodborne pathogen <i>Salmonella</i> is one of the most important and well-studied bacterial pathogens. Recently, whole genome sequence characterizations revealed the presence of multiple novel ADP-ribosylating toxins encoded by a variety of <i>Salmonella</i> serovars. In this review, we discuss both the classical (SpvB) and novel (typhoid toxin, ArtAB, and SboC/SeoC) ADP-ribosylating toxins of <i>Salmonella</i>, including the structure and function of these toxins and our current understanding of their contributions to virulence. |
| first_indexed | 2024-04-14T06:50:30Z |
| format | Article |
| id | doaj.art-848fd01b92fb40a1b51d53899f7f55a6 |
| institution | Directory Open Access Journal |
| issn | 2072-6651 |
| language | English |
| last_indexed | 2024-04-14T06:50:30Z |
| publishDate | 2019-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxins |
| spelling | doaj.art-848fd01b92fb40a1b51d53899f7f55a62022-12-22T02:07:02ZengMDPI AGToxins2072-66512019-07-0111741610.3390/toxins11070416toxins11070416The ADP-Ribosylating Toxins of <i>Salmonella</i>Rachel A. Cheng0Martin Wiedmann1Department of Food Science, Cornell University, Ithaca, NY 14853, USADepartment of Food Science, Cornell University, Ithaca, NY 14853, USAA number of pathogenic bacteria utilize toxins to mediate disease in a susceptible host. The foodborne pathogen <i>Salmonella</i> is one of the most important and well-studied bacterial pathogens. Recently, whole genome sequence characterizations revealed the presence of multiple novel ADP-ribosylating toxins encoded by a variety of <i>Salmonella</i> serovars. In this review, we discuss both the classical (SpvB) and novel (typhoid toxin, ArtAB, and SboC/SeoC) ADP-ribosylating toxins of <i>Salmonella</i>, including the structure and function of these toxins and our current understanding of their contributions to virulence.https://www.mdpi.com/2072-6651/11/7/416ADP-ribosyltransferasetoxinSalmonellaSpvBArtABtyphoid toxinSboCSeoC |
| spellingShingle | Rachel A. Cheng Martin Wiedmann The ADP-Ribosylating Toxins of <i>Salmonella</i> Toxins ADP-ribosyltransferase toxin Salmonella SpvB ArtAB typhoid toxin SboC SeoC |
| title | The ADP-Ribosylating Toxins of <i>Salmonella</i> |
| title_full | The ADP-Ribosylating Toxins of <i>Salmonella</i> |
| title_fullStr | The ADP-Ribosylating Toxins of <i>Salmonella</i> |
| title_full_unstemmed | The ADP-Ribosylating Toxins of <i>Salmonella</i> |
| title_short | The ADP-Ribosylating Toxins of <i>Salmonella</i> |
| title_sort | adp ribosylating toxins of i salmonella i |
| topic | ADP-ribosyltransferase toxin Salmonella SpvB ArtAB typhoid toxin SboC SeoC |
| url | https://www.mdpi.com/2072-6651/11/7/416 |
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