Longitudinal Associations of the Healthy Lifestyle Index Score With Quality of Life in People With Multiple Sclerosis: A Prospective Cohort Study
Objective: To explore the association between combined lifestyle risk factors with quality of life in people with multiple sclerosis (MS) over 2.5 years.Methods: People with MS were recruited to participate in a comprehensive online survey regarding their demographic and clinical characteristics, he...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-11-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fneur.2018.00874/full |
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| author | Teng I. Leong Tracey J. Weiland George A. Jelinek Steve Simpson Steve Simpson Chelsea R. Brown Sandra L. Neate Keryn L. Taylor Emily O'Kearney Elasma Milanzi Alysha M. De Livera Alysha M. De Livera |
| author_facet | Teng I. Leong Tracey J. Weiland George A. Jelinek Steve Simpson Steve Simpson Chelsea R. Brown Sandra L. Neate Keryn L. Taylor Emily O'Kearney Elasma Milanzi Alysha M. De Livera Alysha M. De Livera |
| author_sort | Teng I. Leong |
| collection | DOAJ |
| description | Objective: To explore the association between combined lifestyle risk factors with quality of life in people with multiple sclerosis (MS) over 2.5 years.Methods: People with MS were recruited to participate in a comprehensive online survey regarding their demographic and clinical characteristics, health-related quality of life (HRQOL), and lifestyle behaviors including physical activity, alcohol consumption, cigarette smoking, body mass index, and dietary habits measured at baseline and 2.5-year follow-up. A combined healthy lifestyle index score (HLIS) was constructed by assigning scores of 0–4 to each of the lifestyle risk factors, for which higher values indicate healthier lifestyle behavior. Multivariable linear regression modeling was used to assess whether the HLIS at baseline was associated with the physical and mental HRQOL over the study period in this sample of people with MS.Results: Of 2,466 participants with confirmed MS, 1,401 (57%) completed the follow-up. Multivariable linear regression analyses demonstrated that every 5-point increase (of a possible total of 20) in the baseline HLIS was associated with 1.7 (95% CI: 0.2–3.2) and 2.5 (95% CI: 1.0–4.0) higher scores in the change in physical and mental HRQOL components from baseline to follow-up respectively.Conclusion: Findings suggest the importance of healthy lifestyle behavior in quality of life in MS. A healthy lifestyle program focusing on these behaviors has the potential to positively influence health-related quality of life for people with MS. |
| first_indexed | 2024-12-20T17:24:06Z |
| format | Article |
| id | doaj.art-8491b4dbeeb7454a87cc4eed6208e602 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-12-20T17:24:06Z |
| publishDate | 2018-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-8491b4dbeeb7454a87cc4eed6208e6022022-12-21T19:31:39ZengFrontiers Media S.A.Frontiers in Neurology1664-22952018-11-01910.3389/fneur.2018.00874347500Longitudinal Associations of the Healthy Lifestyle Index Score With Quality of Life in People With Multiple Sclerosis: A Prospective Cohort StudyTeng I. Leong0Tracey J. Weiland1George A. Jelinek2Steve Simpson3Steve Simpson4Chelsea R. Brown5Sandra L. Neate6Keryn L. Taylor7Emily O'Kearney8Elasma Milanzi9Alysha M. De Livera10Alysha M. De Livera11Neuroepidemiology Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, AustraliaNeuroepidemiology Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, AustraliaNeuroepidemiology Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, AustraliaNeuroepidemiology Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, AustraliaMenzies Institute for Medical Research, University of Tasmania, Hobart, TAS, AustraliaNeuroepidemiology Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, AustraliaNeuroepidemiology Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, AustraliaNeuroepidemiology Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, AustraliaNeuroepidemiology Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, AustraliaBiostatistics Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, AustraliaNeuroepidemiology Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, AustraliaBiostatistics Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, AustraliaObjective: To explore the association between combined lifestyle risk factors with quality of life in people with multiple sclerosis (MS) over 2.5 years.Methods: People with MS were recruited to participate in a comprehensive online survey regarding their demographic and clinical characteristics, health-related quality of life (HRQOL), and lifestyle behaviors including physical activity, alcohol consumption, cigarette smoking, body mass index, and dietary habits measured at baseline and 2.5-year follow-up. A combined healthy lifestyle index score (HLIS) was constructed by assigning scores of 0–4 to each of the lifestyle risk factors, for which higher values indicate healthier lifestyle behavior. Multivariable linear regression modeling was used to assess whether the HLIS at baseline was associated with the physical and mental HRQOL over the study period in this sample of people with MS.Results: Of 2,466 participants with confirmed MS, 1,401 (57%) completed the follow-up. Multivariable linear regression analyses demonstrated that every 5-point increase (of a possible total of 20) in the baseline HLIS was associated with 1.7 (95% CI: 0.2–3.2) and 2.5 (95% CI: 1.0–4.0) higher scores in the change in physical and mental HRQOL components from baseline to follow-up respectively.Conclusion: Findings suggest the importance of healthy lifestyle behavior in quality of life in MS. A healthy lifestyle program focusing on these behaviors has the potential to positively influence health-related quality of life for people with MS.https://www.frontiersin.org/article/10.3389/fneur.2018.00874/fullmultiple sclerosislifestylerisk factorsquality of lifeQOLhealth outcomes |
| spellingShingle | Teng I. Leong Tracey J. Weiland George A. Jelinek Steve Simpson Steve Simpson Chelsea R. Brown Sandra L. Neate Keryn L. Taylor Emily O'Kearney Elasma Milanzi Alysha M. De Livera Alysha M. De Livera Longitudinal Associations of the Healthy Lifestyle Index Score With Quality of Life in People With Multiple Sclerosis: A Prospective Cohort Study Frontiers in Neurology multiple sclerosis lifestyle risk factors quality of life QOL health outcomes |
| title | Longitudinal Associations of the Healthy Lifestyle Index Score With Quality of Life in People With Multiple Sclerosis: A Prospective Cohort Study |
| title_full | Longitudinal Associations of the Healthy Lifestyle Index Score With Quality of Life in People With Multiple Sclerosis: A Prospective Cohort Study |
| title_fullStr | Longitudinal Associations of the Healthy Lifestyle Index Score With Quality of Life in People With Multiple Sclerosis: A Prospective Cohort Study |
| title_full_unstemmed | Longitudinal Associations of the Healthy Lifestyle Index Score With Quality of Life in People With Multiple Sclerosis: A Prospective Cohort Study |
| title_short | Longitudinal Associations of the Healthy Lifestyle Index Score With Quality of Life in People With Multiple Sclerosis: A Prospective Cohort Study |
| title_sort | longitudinal associations of the healthy lifestyle index score with quality of life in people with multiple sclerosis a prospective cohort study |
| topic | multiple sclerosis lifestyle risk factors quality of life QOL health outcomes |
| url | https://www.frontiersin.org/article/10.3389/fneur.2018.00874/full |
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