Comparative evaluation of calcium release of the apical plugs formed by mineral trioxide aggregate, Biodentine, and EndoSequence root repair material with and without 2% triple antibiotic powder: An in vitro study
Background: Apical plug formation by mineral trioxide aggregate (MTA), Biodentine, and EndoSequence root repair material (RRM) is an excellent alternative technique to the conventional apexification procedure. Several antimicrobial agents have been incorporated in MTA and Biodentine to boost their a...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Journal of Indian Society of Pedodontics and Preventive Dentistry |
| Subjects: | |
| Online Access: | http://www.jisppd.com/article.asp?issn=0970-4388;year=2020;volume=38;issue=2;spage=132;epage=137;aulast=Mapara |
| _version_ | 1818020396626083840 |
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| author | Pooja Nitin Mapara N D Shashikiran Sachin Gugawad Namrata Gaonkar Savita Hadakar Swapnil Taur Dhanshri Khade |
| author_facet | Pooja Nitin Mapara N D Shashikiran Sachin Gugawad Namrata Gaonkar Savita Hadakar Swapnil Taur Dhanshri Khade |
| author_sort | Pooja Nitin Mapara |
| collection | DOAJ |
| description | Background: Apical plug formation by mineral trioxide aggregate (MTA), Biodentine, and EndoSequence root repair material (RRM) is an excellent alternative technique to the conventional apexification procedure. Several antimicrobial agents have been incorporated in MTA and Biodentine to boost their antimicrobial efficacy. Considering the polymicrobial nature of root canal infection, a combination of potent antimicrobials like triple antibiotic powder (TAP) would be needed to address the diverse flora encountered. Calcium release is the consequential factor in the clinical excellence of these cements. Aim: The aim of the study was to evaluate and compare the calcium released from the apical plugs formed by MTA, Biodentine, and EndoSequence RRM with and without incorporation of 2% TAP. Methods: Ninety single-rooted teeth were divided into (n = 15) Group A: MTA + 2% TAP, Group B: MTA, Group C: Biodentine + 2% TAP, Group D: Biodentine, Group E: EndoSequence RRM + 2% TAP, and Group F: EndoSequence RRM to form the 4 mm apical plugs. Each sample tooth was then immersed in 10 ml of deionized water. Evaluation of calcium release was done on days 7, 15, and 30 using an atomic absorption spectrophotometer. Data were analyzed using one-way analysis of variance, post hoc test, and unpaired t-test. Results: Calcium released was maximum for Group E compared to Group F (P < 0.05), maximum for Group C compared to Group D, and was maximum for Group A compared to Group B (P < 0.05) at days 7, 15 and 30. Conclusion: Incorporation of 2% TAP resulted in increased calcium ions released from MTA, Biodentine, and EndoSequence RRM. |
| first_indexed | 2024-04-14T08:05:24Z |
| format | Article |
| id | doaj.art-8492fa9a47474a79b1190cde06709447 |
| institution | Directory Open Access Journal |
| issn | 0970-4388 1998-3905 |
| language | English |
| last_indexed | 2024-04-14T08:05:24Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Society of Pedodontics and Preventive Dentistry |
| spelling | doaj.art-8492fa9a47474a79b1190cde067094472022-12-22T02:04:47ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Pedodontics and Preventive Dentistry0970-43881998-39052020-01-0138213213710.4103/JISPPD.JISPPD_74_20Comparative evaluation of calcium release of the apical plugs formed by mineral trioxide aggregate, Biodentine, and EndoSequence root repair material with and without 2% triple antibiotic powder: An in vitro studyPooja Nitin MaparaN D ShashikiranSachin GugawadNamrata GaonkarSavita HadakarSwapnil TaurDhanshri KhadeBackground: Apical plug formation by mineral trioxide aggregate (MTA), Biodentine, and EndoSequence root repair material (RRM) is an excellent alternative technique to the conventional apexification procedure. Several antimicrobial agents have been incorporated in MTA and Biodentine to boost their antimicrobial efficacy. Considering the polymicrobial nature of root canal infection, a combination of potent antimicrobials like triple antibiotic powder (TAP) would be needed to address the diverse flora encountered. Calcium release is the consequential factor in the clinical excellence of these cements. Aim: The aim of the study was to evaluate and compare the calcium released from the apical plugs formed by MTA, Biodentine, and EndoSequence RRM with and without incorporation of 2% TAP. Methods: Ninety single-rooted teeth were divided into (n = 15) Group A: MTA + 2% TAP, Group B: MTA, Group C: Biodentine + 2% TAP, Group D: Biodentine, Group E: EndoSequence RRM + 2% TAP, and Group F: EndoSequence RRM to form the 4 mm apical plugs. Each sample tooth was then immersed in 10 ml of deionized water. Evaluation of calcium release was done on days 7, 15, and 30 using an atomic absorption spectrophotometer. Data were analyzed using one-way analysis of variance, post hoc test, and unpaired t-test. Results: Calcium released was maximum for Group E compared to Group F (P < 0.05), maximum for Group C compared to Group D, and was maximum for Group A compared to Group B (P < 0.05) at days 7, 15 and 30. Conclusion: Incorporation of 2% TAP resulted in increased calcium ions released from MTA, Biodentine, and EndoSequence RRM.http://www.jisppd.com/article.asp?issn=0970-4388;year=2020;volume=38;issue=2;spage=132;epage=137;aulast=Maparaapexificationapical plugatomic absorption spectrophotometrybioceramic cementsbiodentinecalcium releaseendosequence root repair materialimmature toothmineral trioxide aggregatetriple antibiotic powder |
| spellingShingle | Pooja Nitin Mapara N D Shashikiran Sachin Gugawad Namrata Gaonkar Savita Hadakar Swapnil Taur Dhanshri Khade Comparative evaluation of calcium release of the apical plugs formed by mineral trioxide aggregate, Biodentine, and EndoSequence root repair material with and without 2% triple antibiotic powder: An in vitro study Journal of Indian Society of Pedodontics and Preventive Dentistry apexification apical plug atomic absorption spectrophotometry bioceramic cements biodentine calcium release endosequence root repair material immature tooth mineral trioxide aggregate triple antibiotic powder |
| title | Comparative evaluation of calcium release of the apical plugs formed by mineral trioxide aggregate, Biodentine, and EndoSequence root repair material with and without 2% triple antibiotic powder: An in vitro study |
| title_full | Comparative evaluation of calcium release of the apical plugs formed by mineral trioxide aggregate, Biodentine, and EndoSequence root repair material with and without 2% triple antibiotic powder: An in vitro study |
| title_fullStr | Comparative evaluation of calcium release of the apical plugs formed by mineral trioxide aggregate, Biodentine, and EndoSequence root repair material with and without 2% triple antibiotic powder: An in vitro study |
| title_full_unstemmed | Comparative evaluation of calcium release of the apical plugs formed by mineral trioxide aggregate, Biodentine, and EndoSequence root repair material with and without 2% triple antibiotic powder: An in vitro study |
| title_short | Comparative evaluation of calcium release of the apical plugs formed by mineral trioxide aggregate, Biodentine, and EndoSequence root repair material with and without 2% triple antibiotic powder: An in vitro study |
| title_sort | comparative evaluation of calcium release of the apical plugs formed by mineral trioxide aggregate biodentine and endosequence root repair material with and without 2 triple antibiotic powder an in vitro study |
| topic | apexification apical plug atomic absorption spectrophotometry bioceramic cements biodentine calcium release endosequence root repair material immature tooth mineral trioxide aggregate triple antibiotic powder |
| url | http://www.jisppd.com/article.asp?issn=0970-4388;year=2020;volume=38;issue=2;spage=132;epage=137;aulast=Mapara |
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