Mycobacterial Aminoglycoside Acetyltransferases: A Little of Drug Resistance, and a Lot of Other Roles

Mycobacterial Aminoglycoside Acetyltransferases: A Little of Drug Resistance, and a Lot of Other Roles

Aminoglycoside acetyltransferases are important determinants of resistance to aminoglycoside antibiotics in most bacterial genera. In mycobacteria, however, aminoglycoside acetyltransferases contribute only partially to aminoglycoside susceptibility since they are related with low level resistance t...

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Bibliographic Details
Main Authors: Fernando Sanz-García, Ernesto Anoz-Carbonell, Esther Pérez-Herrán, Carlos Martín, Ainhoa Lucía, Liliana Rodrigues, José A. Aínsa
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Microbiology
Subjects:
mycobacteria
aminoglycoside antibiotics
aminoglycoside acetyltransferase
drug target
pathogenicity
aminoglycoside resistance
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00046/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00046/full

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