Phosphatidylethanolamine-binding protein 4 deficiency exacerbates carbon tetrachloride-induced liver fibrosis by regulating the NF-κB signaling pathway

Phosphatidylethanolamine-binding protein 4 deficiency exacerbates carbon tetrachloride-induced liver fibrosis by regulating the NF-κB signaling pathway

Liver fibrosis is a pathological process which can progress to hepatocirrhosis, even hepatocellular carcinoma. Phosphatidylethanolamine-binding protein 4 (PEBP4) is a secreted protein involved in regulating many molecular pathways, whereas its roles in diseases including hepatic fibrosis remain unde...

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Bibliographic Details
Main Authors: Qianqian Luo, Yuanyi Ling, Yufei Li, Xiaoqin Qu, Qiaoqing Shi, Shuangyan Zheng, Yanhong Li, Yonghong Huang, Xiaoyan Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
PEBP4
liver fibrosis
NF-κB
mouse model
signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.964829/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.964829/full

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