Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1

Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1

Abstract Invasive lobular carcinoma (ILC) is the most frequent special histological subtype of breast cancer, typically characterized by loss of E‐cadherin. It has clinical features distinct from other estrogen receptor‐positive (ER+) breast cancers but the molecular mechanisms underlying its charac...

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Bibliographic Details
Main Authors: George Sflomos, Laura Battista, Patrick Aouad, Fabio De Martino, Valentina Scabia, Athina Stravodimou, Ayyakkannu Ayyanan, Assia Ifticene‐Treboux, RLS, Philipp Bucher, Maryse Fiche, Giovanna Ambrosini, Cathrin Brisken
Format: Article
Language:English
Published: Springer Nature 2021-03-01
Series:EMBO Molecular Medicine
Subjects:
extracellular matrix
lobular carcinoma
LOXL1
preclinical models
xenografts
Online Access:https://doi.org/10.15252/emmm.202013180

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