Establishment of a protocol to administer immunosuppressive drugs for iPS cell-derived cardiomyocyte patch transplantation in a rat myocardial infarction model

Establishment of a protocol to administer immunosuppressive drugs for iPS cell-derived cardiomyocyte patch transplantation in a rat myocardial infarction model

Abstract Transplantation of human allogeneic induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is a new, promising treatment for severe heart failure. However, immunorejection is a significant concern in allogeneic hiPSC-CM transplantation, requiring the administration of several immu...

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Bibliographic Details
Main Authors:	Emiko Ito, Ai Kawamura, Takuji Kawamura, Maki Takeda, Akima Harada, Noriko Mochizuki-Oda, Yoshiki Sawa, Shigeru Miyagawa
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-06-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-023-37235-5

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