Synthesis and Natural Distribution of Anti-inflammatory Alkamides from Echinacea

The synthesis of the alkamides 2Z,4E-undeca-2,4-dien-8,10-diynoic acid isobutyl amide (1) and 2Z,4E-undeca-2,4-dien-8,10-diynoic acid isobutyl amide (5) was accomplished by organometallic coupling followed by introduction of the doubly unsaturated amide moiety. The distribution of these two amides i...

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Main Authors: Eve Wurtele, Lankun Wu, Jaehoon Bae, George A. Kraus
Format: Article
Language:English
Published: MDPI AG 2006-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/11/10/758/
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author Eve Wurtele
Lankun Wu
Jaehoon Bae
George A. Kraus
author_facet Eve Wurtele
Lankun Wu
Jaehoon Bae
George A. Kraus
author_sort Eve Wurtele
collection DOAJ
description The synthesis of the alkamides 2Z,4E-undeca-2,4-dien-8,10-diynoic acid isobutyl amide (1) and 2Z,4E-undeca-2,4-dien-8,10-diynoic acid isobutyl amide (5) was accomplished by organometallic coupling followed by introduction of the doubly unsaturated amide moiety. The distribution of these two amides in accessions of the nine species of Echinacea was determined.
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spelling doaj.art-849a993d234547ab8d2aa13e11d239392022-12-21T19:48:07ZengMDPI AGMolecules1420-30492006-10-01111075876710.3390/11100758Synthesis and Natural Distribution of Anti-inflammatory Alkamides from EchinaceaEve WurteleLankun WuJaehoon BaeGeorge A. KrausThe synthesis of the alkamides 2Z,4E-undeca-2,4-dien-8,10-diynoic acid isobutyl amide (1) and 2Z,4E-undeca-2,4-dien-8,10-diynoic acid isobutyl amide (5) was accomplished by organometallic coupling followed by introduction of the doubly unsaturated amide moiety. The distribution of these two amides in accessions of the nine species of Echinacea was determined.http://www.mdpi.com/1420-3049/11/10/758/Echinaceaalkamidessynthesis.
spellingShingle Eve Wurtele
Lankun Wu
Jaehoon Bae
George A. Kraus
Synthesis and Natural Distribution of Anti-inflammatory Alkamides from Echinacea
Molecules
Echinacea
alkamides
synthesis.
title Synthesis and Natural Distribution of Anti-inflammatory Alkamides from Echinacea
title_full Synthesis and Natural Distribution of Anti-inflammatory Alkamides from Echinacea
title_fullStr Synthesis and Natural Distribution of Anti-inflammatory Alkamides from Echinacea
title_full_unstemmed Synthesis and Natural Distribution of Anti-inflammatory Alkamides from Echinacea
title_short Synthesis and Natural Distribution of Anti-inflammatory Alkamides from Echinacea
title_sort synthesis and natural distribution of anti inflammatory alkamides from echinacea
topic Echinacea
alkamides
synthesis.
url http://www.mdpi.com/1420-3049/11/10/758/
work_keys_str_mv AT evewurtele synthesisandnaturaldistributionofantiinflammatoryalkamidesfromechinacea
AT lankunwu synthesisandnaturaldistributionofantiinflammatoryalkamidesfromechinacea
AT jaehoonbae synthesisandnaturaldistributionofantiinflammatoryalkamidesfromechinacea
AT georgeakraus synthesisandnaturaldistributionofantiinflammatoryalkamidesfromechinacea