A New Flavone from Erythrina suberosa, its Biological Screening and Application as pH Indicator

A new flavone is isolated, characterized and its pH indicator property is studied for titration between strong/weak acids and bases. Flavone (Z)-3-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-5-(isopentyloxy)-7-methoxy-6-(2-methylpent-1-en-1-yl) chromenylium chloride has been isolated by extracting ether a...

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Main Authors: Mohd Arif Khan Pathan, Abdul Ahad, Mazahar Farooqui
Format: Article
Language:English
Published: Universidade Federal de Mato Grosso do Sul 2019-10-01
Series:Orbital: The Electronic Journal of Chemistry
Subjects:
Online Access:https://periodicos.ufms.br/index.php/orbital/article/view/15875
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author Mohd Arif Khan Pathan
Abdul Ahad
Mazahar Farooqui
author_facet Mohd Arif Khan Pathan
Abdul Ahad
Mazahar Farooqui
author_sort Mohd Arif Khan Pathan
collection DOAJ
description A new flavone is isolated, characterized and its pH indicator property is studied for titration between strong/weak acids and bases. Flavone (Z)-3-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-5-(isopentyloxy)-7-methoxy-6-(2-methylpent-1-en-1-yl) chromenylium chloride has been isolated by extracting ether and methanol. Compound is separated using column chromatography and identified with the help of spectroscopic techniques such as mass, 1HNMR, IR and UV. Compound is also screened for its antibacterial and anti-fungal activity from the flower extract of Erythrina suberosa. Activity of the isolated compound is observed for E Coli bacteria as a gram-negative organism. The compound shows significant color change in acidic and alkaline medium and its potential as pH indicator is encouraging. DOI: http://dx.doi.org/10.17807/orbital.v11i5.1150
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spelling doaj.art-849cde8f5d4d4c8aa30740552cc4a3142023-01-20T10:51:43ZengUniversidade Federal de Mato Grosso do SulOrbital: The Electronic Journal of Chemistry1984-64282019-10-01115A New Flavone from Erythrina suberosa, its Biological Screening and Application as pH IndicatorMohd Arif Khan Pathan0Abdul Ahad1Mazahar Farooqui2Maulana Azad college of Arts, Science and Commerce, Dr Rafiq Zakaria Campus, Rauza Baugh AurangabadDepartment of Chemistry, Maulana Azad college, Dr. Rafiq Zakaria Campus, Aurangabad. MaharashtraDepartment of chemistry, Dr. Rafiq Zakaria college for Women, Navkhanda, Aurangabad. MaharashtraA new flavone is isolated, characterized and its pH indicator property is studied for titration between strong/weak acids and bases. Flavone (Z)-3-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-5-(isopentyloxy)-7-methoxy-6-(2-methylpent-1-en-1-yl) chromenylium chloride has been isolated by extracting ether and methanol. Compound is separated using column chromatography and identified with the help of spectroscopic techniques such as mass, 1HNMR, IR and UV. Compound is also screened for its antibacterial and anti-fungal activity from the flower extract of Erythrina suberosa. Activity of the isolated compound is observed for E Coli bacteria as a gram-negative organism. The compound shows significant color change in acidic and alkaline medium and its potential as pH indicator is encouraging. DOI: http://dx.doi.org/10.17807/orbital.v11i5.1150 https://periodicos.ufms.br/index.php/orbital/article/view/15875anti-bacterialanti-fungal activityerythrina suberosaflavonepH indicator
spellingShingle Mohd Arif Khan Pathan
Abdul Ahad
Mazahar Farooqui
A New Flavone from Erythrina suberosa, its Biological Screening and Application as pH Indicator
Orbital: The Electronic Journal of Chemistry
anti-bacterial
anti-fungal activity
erythrina suberosa
flavone
pH indicator
title A New Flavone from Erythrina suberosa, its Biological Screening and Application as pH Indicator
title_full A New Flavone from Erythrina suberosa, its Biological Screening and Application as pH Indicator
title_fullStr A New Flavone from Erythrina suberosa, its Biological Screening and Application as pH Indicator
title_full_unstemmed A New Flavone from Erythrina suberosa, its Biological Screening and Application as pH Indicator
title_short A New Flavone from Erythrina suberosa, its Biological Screening and Application as pH Indicator
title_sort new flavone from erythrina suberosa its biological screening and application as ph indicator
topic anti-bacterial
anti-fungal activity
erythrina suberosa
flavone
pH indicator
url https://periodicos.ufms.br/index.php/orbital/article/view/15875
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