Peripheral neuropathy associated with monomethyl auristatin E-based antibody-drug conjugates

Summary: Since the successful approval of gemtuzumab ozogamicin, antibody-drug conjugates (ADCs) have emerged as a pivotal category of targeted therapies for cancer. Among these ADCs, the use of monomethyl auristatin E (MMAE) as a payload is prevalent in the development of ADC drugs, which has signi...

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Bibliographic Details
Main Authors: Zhiwen Fu, Chen Gao, Tingting Wu, Lulu Wang, Shijun Li, Yu Zhang, Chen Shi
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223018552

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