Pro- and Anti- Effects of Immunoglobulin A- Producing B Cell in Tumors and Its Triggers

Pro- and Anti- Effects of Immunoglobulin A- Producing B Cell in Tumors and Its Triggers

B cells are well known as key mediators of humoral immune responses via the production of antibodies. Immunoglobulin A (IgA) is the most abundantly produced antibody isotype and provides the first line of immune protection at mucosal surfaces. However, IgA has long been a divisive molecule with resp...

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Bibliographic Details
Main Authors: Ziwen Zhong, Ke Nan, Meilin Weng, Ying Yue, Wenchang Zhou, Zhiqiang Wang, Yiwei Chu, Ronghua Liu, Changhong Miao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
B cells
plasma cells
immunoglobulin A
tumor immunity
class switching
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.765044/full

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