Bim and Bmf synergize to induce apoptosis in Neisseria gonorrhoeae infection.

Bim and Bmf synergize to induce apoptosis in Neisseria gonorrhoeae infection.

Bcl-2 family proteins including the pro-apoptotic BH3-only proteins are central regulators of apoptotic cell death. Here we show by a focused siRNA miniscreen that the synergistic action of the BH3-only proteins Bim and Bmf is required for apoptosis induced by infection with Neisseria gonorrhoeae (N...

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Bibliografski detalji
Glavni autori: Oliver Kepp, Kathleen Gottschalk, Yuri Churin, Krishnaraj Rajalingam, Volker Brinkmann, Nikolaus Machuy, Guido Kroemer, Thomas Rudel
Format: Članak
Jezik:English
Izdano: Public Library of Science (PLoS) 2009-03-01
Serija:PLoS Pathogens
Online pristup:http://europepmc.org/articles/PMC2654407?pdf=render

Internet

http://europepmc.org/articles/PMC2654407?pdf=render

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