Identification of UDP-Glucuronosyltransferase 2B15 (UGT2B15) as a Target for IGF1 and Insulin Action

Identification of UDP-Glucuronosyltransferase 2B15 (UGT2B15) as a Target for IGF1 and Insulin Action

Normal growth and development in mammals are tightly controlled by numerous genetic factors and metabolic conditions. The growth hormone (GH)-insulin-like growth factor-1 (IGF1) hormonal axis is a key player in the regulation of these processes. Dysregulation of the GH-IGF1 endocrine system is linke...

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Bibliographic Details
Main Authors: Rive Sarfstein, Karthik Nagaraj, Shivang Parikh, Carmit Levy, Zvi Laron, Dafna Benayahu, Haim Werner
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
insulin-like growth factor-1 (IGF1)
growth hormone receptor
UGT2B15
Laron syndrome
p53
Online Access:https://www.mdpi.com/2073-4409/11/10/1627

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