Cardiovascular Toxicities of Radiation Therapy and Recommended Screening and Surveillance

Radiation therapy is a key part of treatment for many cancers. Vast advancements in the field of radiation oncology have led to a decrease in malignancy-related mortality, which has uncovered some of the long-term side effects of radiation therapy. Specifically, there has been an increase in researc...

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Main Authors: Gabriela Narowska, Sakshi Gandhi, Allison Tzeng, Eman A. Hamad
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/10/11/447
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author Gabriela Narowska
Sakshi Gandhi
Allison Tzeng
Eman A. Hamad
author_facet Gabriela Narowska
Sakshi Gandhi
Allison Tzeng
Eman A. Hamad
author_sort Gabriela Narowska
collection DOAJ
description Radiation therapy is a key part of treatment for many cancers. Vast advancements in the field of radiation oncology have led to a decrease in malignancy-related mortality, which has uncovered some of the long-term side effects of radiation therapy. Specifically, there has been an increase in research looking into the cardiovascular side effects of chest radiation therapy for cancers of the esophagus, breast, and lung tissue as well as lymphomas. The manifestations of cardiac injury from irradiation range from short-term complications, such as pericarditis, to long-term damage including cardiomyopathy, valvular disease, and conduction disturbances. The aims of this article are to describe the cardiovascular side effects and the associated risk factors, to discuss risk reduction strategies, and to provide guidance in pre-radiation screening, post-radiation surveillance, and the management of these conditions.
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spelling doaj.art-84a09ccbc0e94452a4779c4162e89dad2023-11-24T14:48:48ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252023-10-01101144710.3390/jcdd10110447Cardiovascular Toxicities of Radiation Therapy and Recommended Screening and SurveillanceGabriela Narowska0Sakshi Gandhi1Allison Tzeng2Eman A. Hamad3Department of Cardiology, Temple University Hospital, Philadelphia, PA 19140, USADepartment of Cardiology, Temple University Hospital, Philadelphia, PA 19140, USADepartment of Cardiology, Temple University Hospital, Philadelphia, PA 19140, USADepartment of Cardiology, Temple University Hospital, Philadelphia, PA 19140, USARadiation therapy is a key part of treatment for many cancers. Vast advancements in the field of radiation oncology have led to a decrease in malignancy-related mortality, which has uncovered some of the long-term side effects of radiation therapy. Specifically, there has been an increase in research looking into the cardiovascular side effects of chest radiation therapy for cancers of the esophagus, breast, and lung tissue as well as lymphomas. The manifestations of cardiac injury from irradiation range from short-term complications, such as pericarditis, to long-term damage including cardiomyopathy, valvular disease, and conduction disturbances. The aims of this article are to describe the cardiovascular side effects and the associated risk factors, to discuss risk reduction strategies, and to provide guidance in pre-radiation screening, post-radiation surveillance, and the management of these conditions.https://www.mdpi.com/2308-3425/10/11/447radiationcardiotoxicityscreeningpreventionsurveillanceconstrictive pericarditis
spellingShingle Gabriela Narowska
Sakshi Gandhi
Allison Tzeng
Eman A. Hamad
Cardiovascular Toxicities of Radiation Therapy and Recommended Screening and Surveillance
Journal of Cardiovascular Development and Disease
radiation
cardiotoxicity
screening
prevention
surveillance
constrictive pericarditis
title Cardiovascular Toxicities of Radiation Therapy and Recommended Screening and Surveillance
title_full Cardiovascular Toxicities of Radiation Therapy and Recommended Screening and Surveillance
title_fullStr Cardiovascular Toxicities of Radiation Therapy and Recommended Screening and Surveillance
title_full_unstemmed Cardiovascular Toxicities of Radiation Therapy and Recommended Screening and Surveillance
title_short Cardiovascular Toxicities of Radiation Therapy and Recommended Screening and Surveillance
title_sort cardiovascular toxicities of radiation therapy and recommended screening and surveillance
topic radiation
cardiotoxicity
screening
prevention
surveillance
constrictive pericarditis
url https://www.mdpi.com/2308-3425/10/11/447
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AT allisontzeng cardiovasculartoxicitiesofradiationtherapyandrecommendedscreeningandsurveillance
AT emanahamad cardiovasculartoxicitiesofradiationtherapyandrecommendedscreeningandsurveillance