Phage single-stranded DNA-binding protein or host DNA damage triggers the activation of the AbpAB phage defense system

Phage single-stranded DNA-binding protein or host DNA damage triggers the activation of the AbpAB phage defense system

ABSTRACTBacteria have developed various defense mechanisms against phages. Abortive infection (Abi), a bacterial defense mechanism, can be achieved through various means, including toxin-antitoxin systems, cyclic oligonucleotide-based antiphage signaling systems, and retrons. AbpA and AbpB (AbpAB) d...

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Bibliographic Details
Main Authors: Takaomi Sasaki, Saya Takita, Takashi Fujishiro, Yunosuke Shintani, Satoki Nojiri, Ryota Yasui, Tetsuro Yonesaki, Yuichi Otsuka
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mSphere
Subjects:
bacteriophages
Escherichia coli
phage defense system
AbpA-AbpB
Online Access:https://journals.asm.org/doi/10.1128/msphere.00372-23

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