Descending necrotizing mediastinitis of oropharyngeal infections
Background and aims. Descending necrotizing mediastinitis (DNM) is a rare and life-threatening infection. Management of this condition is very difficult and before 1990s, DNM had a mortality rate of 40% despite the use of antibiotics. One of the etiologies of this condition is rapid downward spread...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tabriz University of Medical Sciences
2009-09-01
|
| Series: | Journal of Dental Research, Dental Clinics, Dental Prospects |
| Online Access: | http://dentistry.tbzmed.ac.ir/joddd/index.php/joddd/article/view/93 |
| _version_ | 1828438023436500992 |
|---|---|
| author | Mohsen Sokouti Saeed Nezafati |
| author_facet | Mohsen Sokouti Saeed Nezafati |
| author_sort | Mohsen Sokouti |
| collection | DOAJ |
| description | Background and aims. Descending necrotizing mediastinitis (DNM) is a rare and life-threatening infection. Management of this condition is very difficult and before 1990s, DNM had a mortality rate of 40% despite the use of antibiotics. One of the etiologies of this condition is rapid downward spread of oropharyngeal infection along the cervical fascia planes into the mediastinum. Materials and methods. Patients with DNM from odontogenic, peritonsillar and retropharyngeal origins, who underwent surgical treatment from 1990 to 2007, were reviewed. Data extracted from medical records of the patients included age, gender, origin of the infection, surgical approaches, and the cause of mortality. Descriptive data were expressed as a Mean ± SE. Results. Thirteen patients aged 15 to 56 (mean, 34.5 years old; 8 males and 5 females) were studied. The origins of infection included odontogenic abscess in 10 cases and peritonsillar and retropharyngeal abscess in 3 patients. The mean duration from onset of symptoms to the surgery was 12.18 ± 0.98 days (range 3 to 24 days) and the mean duration from initial surgery to discharges was 28.51 ± 3.25 days (range 5 to 92 days). Post-operative mortality was seen in three patients. Conclusion. Descending necrotizing mediastinitis can arise from odontogenic abscesses and must be detected as early as possible, as it is a life-threatening infection. |
| first_indexed | 2024-12-10T19:56:41Z |
| format | Article |
| id | doaj.art-84a4e688529b4e059e93bba6a251a054 |
| institution | Directory Open Access Journal |
| issn | 2008-210X 2008-2118 |
| language | English |
| last_indexed | 2024-12-10T19:56:41Z |
| publishDate | 2009-09-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Dental Research, Dental Clinics, Dental Prospects |
| spelling | doaj.art-84a4e688529b4e059e93bba6a251a0542022-12-22T01:35:38ZengTabriz University of Medical SciencesJournal of Dental Research, Dental Clinics, Dental Prospects2008-210X2008-21182009-09-01338285Descending necrotizing mediastinitis of oropharyngeal infectionsMohsen SokoutiSaeed NezafatiBackground and aims. Descending necrotizing mediastinitis (DNM) is a rare and life-threatening infection. Management of this condition is very difficult and before 1990s, DNM had a mortality rate of 40% despite the use of antibiotics. One of the etiologies of this condition is rapid downward spread of oropharyngeal infection along the cervical fascia planes into the mediastinum. Materials and methods. Patients with DNM from odontogenic, peritonsillar and retropharyngeal origins, who underwent surgical treatment from 1990 to 2007, were reviewed. Data extracted from medical records of the patients included age, gender, origin of the infection, surgical approaches, and the cause of mortality. Descriptive data were expressed as a Mean ± SE. Results. Thirteen patients aged 15 to 56 (mean, 34.5 years old; 8 males and 5 females) were studied. The origins of infection included odontogenic abscess in 10 cases and peritonsillar and retropharyngeal abscess in 3 patients. The mean duration from onset of symptoms to the surgery was 12.18 ± 0.98 days (range 3 to 24 days) and the mean duration from initial surgery to discharges was 28.51 ± 3.25 days (range 5 to 92 days). Post-operative mortality was seen in three patients. Conclusion. Descending necrotizing mediastinitis can arise from odontogenic abscesses and must be detected as early as possible, as it is a life-threatening infection.http://dentistry.tbzmed.ac.ir/joddd/index.php/joddd/article/view/93 |
| spellingShingle | Mohsen Sokouti Saeed Nezafati Descending necrotizing mediastinitis of oropharyngeal infections Journal of Dental Research, Dental Clinics, Dental Prospects |
| title | Descending necrotizing mediastinitis of oropharyngeal infections |
| title_full | Descending necrotizing mediastinitis of oropharyngeal infections |
| title_fullStr | Descending necrotizing mediastinitis of oropharyngeal infections |
| title_full_unstemmed | Descending necrotizing mediastinitis of oropharyngeal infections |
| title_short | Descending necrotizing mediastinitis of oropharyngeal infections |
| title_sort | descending necrotizing mediastinitis of oropharyngeal infections |
| url | http://dentistry.tbzmed.ac.ir/joddd/index.php/joddd/article/view/93 |
| work_keys_str_mv | AT mohsensokouti descendingnecrotizingmediastinitisoforopharyngealinfections AT saeednezafati descendingnecrotizingmediastinitisoforopharyngealinfections |