Obesity Not Necessary, Risk of Symptomatic Cholelithiasis Increases as a Function of BMI
Introduction: Obesity is a well-established risk factor for cholelithiasis. But most of the studies have actually tried to establish the risk of cholelithiasis in overweight and obese people. Very few studies have addressed the issue of cholelithiasis in patients with otherwise normal Body Mass...
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| Format: | Article |
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JCDR Research and Publications Private Limited
2016-10-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/8736/22098_CE(RA1)_F(T)_PF1(Aa_RK)_PFA(P)_PF2(PAG).pdf |
| _version_ | 1818151121965809664 |
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| author | Bikram Kharga Barun Kumar Sharma Varun Kumar Singh Kumar Nishant Phuchungla Bhutia Roshan Tamang Nitin Jain |
| author_facet | Bikram Kharga Barun Kumar Sharma Varun Kumar Singh Kumar Nishant Phuchungla Bhutia Roshan Tamang Nitin Jain |
| author_sort | Bikram Kharga |
| collection | DOAJ |
| description | Introduction: Obesity is a well-established risk factor for
cholelithiasis. But most of the studies have actually tried
to establish the risk of cholelithiasis in overweight and
obese people. Very few studies have addressed the issue of
cholelithiasis in patients with otherwise normal Body Mass
Index (BMI). In this study we have tried to establish if there is
any relationship between increasing BMI and cholelithiasis.
Aim: To establish a relationship between increasing BMI and
risk of cholelithiasis.
Materials and Methods: Retrospective analysis was carried out
after doing a prospective pilot study. Ten years data of patients
admitted to surgery ward with complaints of pain abdomen
was reviewed. Patients with cholelithiasis were segregated as
cases and patients with some other diagnosis were selected
as controls. Patients with incidental diagnosis of cholelithiasis
were excluded. Appropriate analytical tools were used to draw
the results using SPSS© 20.
Results: Over 11,000 patients data was reviewed and 7,182
patients were selected for inclusion into the study. Major exclusion was due to incomplete availability of data. Cholelithiasis
group had 2,872 patients and rest of the patients served as
controls against them. Female patients outnumbered their male
counterparts in cholelithiasis group. Mean age of the gallstone
patients was 37.09 years, almost 2 years younger than their
controls. Mean BMI of all patients was 23.55 kg/m2
and in
cholelithiasis and control group was 24.93 and 22.62, respectively
(df=1, F>1635.395, p<0.001). Gender specific comparison also
yielded a significant difference df=3, F=547.238, p<0.001). The
difference in the way the patients were distributed among the
ethnic groups (Nepalis, Bhutias, Lepchas and others) was also
significant (df=3, F=34.234, p<0.001). Most important outcome
was that the majority of the patients in the cholelithiasis group
were within the normal BMI range.
Conclusion: We concluded that it’s not only the overweight
or obese patients who develop symptomatic cholelithiasis but
also the individuals with normal BMI. The risk of symptomatic
cholelithiasis increases with every increase in BMI. Risk of
symptomatic cholelithiasis also increases in women and as the
age advances. |
| first_indexed | 2024-12-11T13:33:48Z |
| format | Article |
| id | doaj.art-84a5ee02ee3b47118b4efcd0ee6849d7 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-11T13:33:48Z |
| publishDate | 2016-10-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-84a5ee02ee3b47118b4efcd0ee6849d72022-12-22T01:05:10ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-10-011010PC28PC3210.7860/JCDR/2016/22098.8736Obesity Not Necessary, Risk of Symptomatic Cholelithiasis Increases as a Function of BMIBikram Kharga0Barun Kumar Sharma1Varun Kumar Singh2Kumar Nishant3Phuchungla Bhutia4Roshan Tamang5Nitin Jain6Associate Professor, Department of Surgery, Sikkim Manipal Institute of Medical Sciences, Sikkim, Gangtok, India.Associate Professor, Department of Radiology, Sikkim Manipal Institute of Medical Sciences, Sikkim, Gangtok, India.Assistant Professor, Department of Surgery, Sikkim Manipal Institute of Medical Sciences, Sikkim, Gangtok, India.Associate Professor, Department of Surgery, Sikkim Manipal Institute of Medical Sciences, Sikkim, Gangtok, India.Assistant Professor, Department of Surgery, Sikkim Manipal Institute of Medical Sciences, Sikkim, Gangtok, India.Assistant Professor, Department of Surgery, Sikkim Manipal Institute of Medical Sciences, Sikkim, Gangtok, India.Senior Resident, Department of Surgery, Sikkim Manipal Institute of Medical Sciences, Sikkim, Gangtok, India.Introduction: Obesity is a well-established risk factor for cholelithiasis. But most of the studies have actually tried to establish the risk of cholelithiasis in overweight and obese people. Very few studies have addressed the issue of cholelithiasis in patients with otherwise normal Body Mass Index (BMI). In this study we have tried to establish if there is any relationship between increasing BMI and cholelithiasis. Aim: To establish a relationship between increasing BMI and risk of cholelithiasis. Materials and Methods: Retrospective analysis was carried out after doing a prospective pilot study. Ten years data of patients admitted to surgery ward with complaints of pain abdomen was reviewed. Patients with cholelithiasis were segregated as cases and patients with some other diagnosis were selected as controls. Patients with incidental diagnosis of cholelithiasis were excluded. Appropriate analytical tools were used to draw the results using SPSS© 20. Results: Over 11,000 patients data was reviewed and 7,182 patients were selected for inclusion into the study. Major exclusion was due to incomplete availability of data. Cholelithiasis group had 2,872 patients and rest of the patients served as controls against them. Female patients outnumbered their male counterparts in cholelithiasis group. Mean age of the gallstone patients was 37.09 years, almost 2 years younger than their controls. Mean BMI of all patients was 23.55 kg/m2 and in cholelithiasis and control group was 24.93 and 22.62, respectively (df=1, F>1635.395, p<0.001). Gender specific comparison also yielded a significant difference df=3, F=547.238, p<0.001). The difference in the way the patients were distributed among the ethnic groups (Nepalis, Bhutias, Lepchas and others) was also significant (df=3, F=34.234, p<0.001). Most important outcome was that the majority of the patients in the cholelithiasis group were within the normal BMI range. Conclusion: We concluded that it’s not only the overweight or obese patients who develop symptomatic cholelithiasis but also the individuals with normal BMI. The risk of symptomatic cholelithiasis increases with every increase in BMI. Risk of symptomatic cholelithiasis also increases in women and as the age advances.https://jcdr.net/articles/PDF/8736/22098_CE(RA1)_F(T)_PF1(Aa_RK)_PFA(P)_PF2(PAG).pdfcholecystectomygall bladdergallstones |
| spellingShingle | Bikram Kharga Barun Kumar Sharma Varun Kumar Singh Kumar Nishant Phuchungla Bhutia Roshan Tamang Nitin Jain Obesity Not Necessary, Risk of Symptomatic Cholelithiasis Increases as a Function of BMI Journal of Clinical and Diagnostic Research cholecystectomy gall bladder gallstones |
| title | Obesity Not Necessary, Risk of Symptomatic Cholelithiasis Increases as a Function of BMI |
| title_full | Obesity Not Necessary, Risk of Symptomatic Cholelithiasis Increases as a Function of BMI |
| title_fullStr | Obesity Not Necessary, Risk of Symptomatic Cholelithiasis Increases as a Function of BMI |
| title_full_unstemmed | Obesity Not Necessary, Risk of Symptomatic Cholelithiasis Increases as a Function of BMI |
| title_short | Obesity Not Necessary, Risk of Symptomatic Cholelithiasis Increases as a Function of BMI |
| title_sort | obesity not necessary risk of symptomatic cholelithiasis increases as a function of bmi |
| topic | cholecystectomy gall bladder gallstones |
| url | https://jcdr.net/articles/PDF/8736/22098_CE(RA1)_F(T)_PF1(Aa_RK)_PFA(P)_PF2(PAG).pdf |
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