A Comprehensive Review of Daridorexant, a Dual-Orexin Receptor Antagonist as New Approach for the Treatment of Insomnia

A Comprehensive Review of Daridorexant, a Dual-Orexin Receptor Antagonist as New Approach for the Treatment of Insomnia

Insomnia affects 4.4–4.8% of the world’s population, but because the effect of hypnotic drugs is limited and may cause harmful side-effects, scientists are turning their attention to developing drugs that act on the orexin system. Daridorexant, a selective dual-orexin receptor antagonist (DORA), has...

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Bibliographic Details
Main Authors: Wojciech Ziemichód, Karolina Grabowska, Antonina Kurowska, Grażyna Biała
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
daridorexant
insomnia
DORA
orexin system
orexin antagonists
Online Access:https://www.mdpi.com/1420-3049/27/18/6041

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