Synthetic molecular recognition nanosensor paint for microalbuminuria

Microalbuminuria, a clinical marker associated with cancer and hypertension, defined by low albumin levels in the urine, is normally detected by immunoassay. Herein, a nanosensor paint was developed using a polymer to mimic fatty acid binding to albumin, transduced by carbon nanotube fluorescence.

Bibliographic Details
Main Authors: Januka Budhathoki-Uprety, Janki Shah, Joshua A. Korsen, Alysandria E. Wayne, Thomas V. Galassi, Joseph R. Cohen, Jackson D. Harvey, Prakrit V. Jena, Lakshmi V. Ramanathan, Edgar A. Jaimes, Daniel A. Heller
Format: Article
Language:English
Published: Nature Portfolio 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11583-1
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author Januka Budhathoki-Uprety
Janki Shah
Joshua A. Korsen
Alysandria E. Wayne
Thomas V. Galassi
Joseph R. Cohen
Jackson D. Harvey
Prakrit V. Jena
Lakshmi V. Ramanathan
Edgar A. Jaimes
Daniel A. Heller
author_facet Januka Budhathoki-Uprety
Janki Shah
Joshua A. Korsen
Alysandria E. Wayne
Thomas V. Galassi
Joseph R. Cohen
Jackson D. Harvey
Prakrit V. Jena
Lakshmi V. Ramanathan
Edgar A. Jaimes
Daniel A. Heller
author_sort Januka Budhathoki-Uprety
collection DOAJ
description Microalbuminuria, a clinical marker associated with cancer and hypertension, defined by low albumin levels in the urine, is normally detected by immunoassay. Herein, a nanosensor paint was developed using a polymer to mimic fatty acid binding to albumin, transduced by carbon nanotube fluorescence.
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spelling doaj.art-84ad4bc60aee45148a7ef379969a0af82022-12-21T19:27:18ZengNature PortfolioNature Communications2041-17232019-08-011011910.1038/s41467-019-11583-1Synthetic molecular recognition nanosensor paint for microalbuminuriaJanuka Budhathoki-Uprety0Janki Shah1Joshua A. Korsen2Alysandria E. Wayne3Thomas V. Galassi4Joseph R. Cohen5Jackson D. Harvey6Prakrit V. Jena7Lakshmi V. Ramanathan8Edgar A. Jaimes9Daniel A. Heller10Memorial Sloan Kettering Cancer CenterMemorial Sloan Kettering Cancer CenterMemorial Sloan Kettering Cancer CenterMemorial Sloan Kettering Cancer CenterMemorial Sloan Kettering Cancer CenterMemorial Sloan Kettering Cancer CenterMemorial Sloan Kettering Cancer CenterMemorial Sloan Kettering Cancer CenterMemorial Sloan Kettering Cancer CenterMemorial Sloan Kettering Cancer CenterMemorial Sloan Kettering Cancer CenterMicroalbuminuria, a clinical marker associated with cancer and hypertension, defined by low albumin levels in the urine, is normally detected by immunoassay. Herein, a nanosensor paint was developed using a polymer to mimic fatty acid binding to albumin, transduced by carbon nanotube fluorescence.https://doi.org/10.1038/s41467-019-11583-1
spellingShingle Januka Budhathoki-Uprety
Janki Shah
Joshua A. Korsen
Alysandria E. Wayne
Thomas V. Galassi
Joseph R. Cohen
Jackson D. Harvey
Prakrit V. Jena
Lakshmi V. Ramanathan
Edgar A. Jaimes
Daniel A. Heller
Synthetic molecular recognition nanosensor paint for microalbuminuria
Nature Communications
title Synthetic molecular recognition nanosensor paint for microalbuminuria
title_full Synthetic molecular recognition nanosensor paint for microalbuminuria
title_fullStr Synthetic molecular recognition nanosensor paint for microalbuminuria
title_full_unstemmed Synthetic molecular recognition nanosensor paint for microalbuminuria
title_short Synthetic molecular recognition nanosensor paint for microalbuminuria
title_sort synthetic molecular recognition nanosensor paint for microalbuminuria
url https://doi.org/10.1038/s41467-019-11583-1
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