Synthesis and biological activity of three new 5a-hydroxy spirostanic brassinosteroid analogues
Three new spirostanic brassinosteroid analogues have been synthesized for the first time from diosgenin: (25R)-2alpha,3alpha-epoxy-5alpha-hydroxyspirostan-6-one (3), (25R)-2beta,3alpha,5alpha-trihydroxyspirostan-6-one (5) and (25R)-2beta-methoxy-3alpha,5alpha-dihydroxyspirostan-6-one (6). In the rad...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Química
2003-01-01
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| Series: | Journal of the Brazilian Chemical Society |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532003000300022 |
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| author | Rodríguez Caridad R. Villalobos Yohan I. Becerra Esther A. Manchado Francisco C. Herrera Deysma C. Zullo Marco A. T. |
| author_facet | Rodríguez Caridad R. Villalobos Yohan I. Becerra Esther A. Manchado Francisco C. Herrera Deysma C. Zullo Marco A. T. |
| author_sort | Rodríguez Caridad R. |
| collection | DOAJ |
| description | Three new spirostanic brassinosteroid analogues have been synthesized for the first time from diosgenin: (25R)-2alpha,3alpha-epoxy-5alpha-hydroxyspirostan-6-one (3), (25R)-2beta,3alpha,5alpha-trihydroxyspirostan-6-one (5) and (25R)-2beta-methoxy-3alpha,5alpha-dihydroxyspirostan-6-one (6). In the radish hypocotyl elongation and cotyledon expansion bioassay compound 3 showed plant growth promoting activity whereas 6 was shown to be phytotoxic. |
| first_indexed | 2024-12-21T08:19:06Z |
| format | Article |
| id | doaj.art-84b2a7dd0c334780b7a71dab18a44a74 |
| institution | Directory Open Access Journal |
| issn | 0103-5053 |
| language | English |
| last_indexed | 2024-12-21T08:19:06Z |
| publishDate | 2003-01-01 |
| publisher | Sociedade Brasileira de Química |
| record_format | Article |
| series | Journal of the Brazilian Chemical Society |
| spelling | doaj.art-84b2a7dd0c334780b7a71dab18a44a742022-12-21T19:10:29ZengSociedade Brasileira de QuímicaJournal of the Brazilian Chemical Society0103-50532003-01-01143466469Synthesis and biological activity of three new 5a-hydroxy spirostanic brassinosteroid analoguesRodríguez Caridad R.Villalobos Yohan I.Becerra Esther A.Manchado Francisco C.Herrera Deysma C.Zullo Marco A. T.Three new spirostanic brassinosteroid analogues have been synthesized for the first time from diosgenin: (25R)-2alpha,3alpha-epoxy-5alpha-hydroxyspirostan-6-one (3), (25R)-2beta,3alpha,5alpha-trihydroxyspirostan-6-one (5) and (25R)-2beta-methoxy-3alpha,5alpha-dihydroxyspirostan-6-one (6). In the radish hypocotyl elongation and cotyledon expansion bioassay compound 3 showed plant growth promoting activity whereas 6 was shown to be phytotoxic.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532003000300022steroidsbrassinosteroid analoguesdiosgenin |
| spellingShingle | Rodríguez Caridad R. Villalobos Yohan I. Becerra Esther A. Manchado Francisco C. Herrera Deysma C. Zullo Marco A. T. Synthesis and biological activity of three new 5a-hydroxy spirostanic brassinosteroid analogues Journal of the Brazilian Chemical Society steroids brassinosteroid analogues diosgenin |
| title | Synthesis and biological activity of three new 5a-hydroxy spirostanic brassinosteroid analogues |
| title_full | Synthesis and biological activity of three new 5a-hydroxy spirostanic brassinosteroid analogues |
| title_fullStr | Synthesis and biological activity of three new 5a-hydroxy spirostanic brassinosteroid analogues |
| title_full_unstemmed | Synthesis and biological activity of three new 5a-hydroxy spirostanic brassinosteroid analogues |
| title_short | Synthesis and biological activity of three new 5a-hydroxy spirostanic brassinosteroid analogues |
| title_sort | synthesis and biological activity of three new 5a hydroxy spirostanic brassinosteroid analogues |
| topic | steroids brassinosteroid analogues diosgenin |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532003000300022 |
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