Single-particle cryo-EM using alignment by classification (ABC): the structure of Lumbricus terrestris haemoglobin

Single-particle cryo-EM using alignment by classification (ABC): the structure of Lumbricus terrestris haemoglobin

Single-particle cryogenic electron microscopy (cryo-EM) can now yield near-atomic resolution structures of biological complexes. However, the reference-based alignment algorithms commonly used in cryo-EM suffer from reference bias, limiting their applicability (also known as the `Einstein from rando...

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Bibliographic Details
Main Authors: Pavel Afanasyev, Charlotte Seer-Linnemayr, Raimond B. G. Ravelli, Rishi Matadeen, Sacha De Carlo, Bart Alewijnse, Rodrigo V. Portugal, Navraj S. Pannu, Michael Schatz, Marin van Heel
Format: Article
Language:English
Published: International Union of Crystallography 2017-09-01
Series:IUCrJ
Subjects:
alignment by classification
angular reconstitution
MSA
worm haemoglobin
cryo-EM
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252517010922

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