Central neck lymph node metastasis in oral squamous cell carcinoma at the floor of mouth
Abstracts Background Our goal was to analyze the incidence of level VI metastasis in previously untreated oral squamous cell carcinoma (SCC) patients and their clinicopathological and prognostic characteristics. Methods Oral SCC patients with level VI metastasis were retrospectively enrolled, and th...
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| Format: | Article |
| Language: | English |
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BMC
2021-03-01
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| Series: | BMC Cancer |
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| Online Access: | https://doi.org/10.1186/s12885-021-07958-7 |
| _version_ | 1818576695779655680 |
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| author | Songtao Zhang Runfang Zhang Chao Wang Wenbo Gong Miaomiao Xue Lina Liu Yuanyuan Zhang |
| author_facet | Songtao Zhang Runfang Zhang Chao Wang Wenbo Gong Miaomiao Xue Lina Liu Yuanyuan Zhang |
| author_sort | Songtao Zhang |
| collection | DOAJ |
| description | Abstracts Background Our goal was to analyze the incidence of level VI metastasis in previously untreated oral squamous cell carcinoma (SCC) patients and their clinicopathological and prognostic characteristics. Methods Oral SCC patients with level VI metastasis were retrospectively enrolled, and their demographic and pathologic features as well as their survival data were descriptively analyzed. Results A total of 13 cases from 1875 patients were included, all patients had SCC at the floor of mouth (SCCFOM). Eight (61.5%) patients had a pT4 tumor, and all patients had a pathological N3 neck with multiple positive lymph nodes. Adverse pathologic features were present in 100% of the patients. The size of the metastatic foci in level VI ranged from 2.6 cm to 4.5 cm with a mean value of 3.2 cm, and 5 patients showed a soft tissue deposit with no lymph node component. Recurrence occurred in all patients, and 11 patients died of uncontrolled cancer within 5 years after surgery. Conclusion Level VI metastasis in primary oral SCCFOM is rare, and its prognosis is poor. |
| first_indexed | 2024-12-16T06:18:07Z |
| format | Article |
| id | doaj.art-84b7357003ec49538cad5386bc8e22a6 |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-12-16T06:18:07Z |
| publishDate | 2021-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-84b7357003ec49538cad5386bc8e22a62022-12-21T22:41:13ZengBMCBMC Cancer1471-24072021-03-012111710.1186/s12885-021-07958-7Central neck lymph node metastasis in oral squamous cell carcinoma at the floor of mouthSongtao Zhang0Runfang Zhang1Chao Wang2Wenbo Gong3Miaomiao Xue4Lina Liu5Yuanyuan Zhang6Department of Thyroid Head and Neck Surgery, Affiliated Tumor Hospital of Zhengzhou UniversityDepartment of Thyroid Head and Neck Surgery, Affiliated Tumor Hospital of Zhengzhou UniversityDepartment of Thyroid Head and Neck Surgery, Affiliated Tumor Hospital of Zhengzhou UniversityDepartment of Thyroid Head and Neck Surgery, Affiliated Tumor Hospital of Zhengzhou UniversityDepartment of General Dentistry, The First Affiliated Hospital of Zhengzhou UniversityDepartment of General Dentistry, The First Affiliated Hospital of Zhengzhou UniversityDepartment of General Dentistry, The First Affiliated Hospital of Zhengzhou UniversityAbstracts Background Our goal was to analyze the incidence of level VI metastasis in previously untreated oral squamous cell carcinoma (SCC) patients and their clinicopathological and prognostic characteristics. Methods Oral SCC patients with level VI metastasis were retrospectively enrolled, and their demographic and pathologic features as well as their survival data were descriptively analyzed. Results A total of 13 cases from 1875 patients were included, all patients had SCC at the floor of mouth (SCCFOM). Eight (61.5%) patients had a pT4 tumor, and all patients had a pathological N3 neck with multiple positive lymph nodes. Adverse pathologic features were present in 100% of the patients. The size of the metastatic foci in level VI ranged from 2.6 cm to 4.5 cm with a mean value of 3.2 cm, and 5 patients showed a soft tissue deposit with no lymph node component. Recurrence occurred in all patients, and 11 patients died of uncontrolled cancer within 5 years after surgery. Conclusion Level VI metastasis in primary oral SCCFOM is rare, and its prognosis is poor.https://doi.org/10.1186/s12885-021-07958-7Level VI metastasisOral squamous cell carcinomaHead and neck squamous cell carcinomaCentral neck metastasisNeck lymph node metastasis |
| spellingShingle | Songtao Zhang Runfang Zhang Chao Wang Wenbo Gong Miaomiao Xue Lina Liu Yuanyuan Zhang Central neck lymph node metastasis in oral squamous cell carcinoma at the floor of mouth BMC Cancer Level VI metastasis Oral squamous cell carcinoma Head and neck squamous cell carcinoma Central neck metastasis Neck lymph node metastasis |
| title | Central neck lymph node metastasis in oral squamous cell carcinoma at the floor of mouth |
| title_full | Central neck lymph node metastasis in oral squamous cell carcinoma at the floor of mouth |
| title_fullStr | Central neck lymph node metastasis in oral squamous cell carcinoma at the floor of mouth |
| title_full_unstemmed | Central neck lymph node metastasis in oral squamous cell carcinoma at the floor of mouth |
| title_short | Central neck lymph node metastasis in oral squamous cell carcinoma at the floor of mouth |
| title_sort | central neck lymph node metastasis in oral squamous cell carcinoma at the floor of mouth |
| topic | Level VI metastasis Oral squamous cell carcinoma Head and neck squamous cell carcinoma Central neck metastasis Neck lymph node metastasis |
| url | https://doi.org/10.1186/s12885-021-07958-7 |
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