Volumetric Changes of a Customized Allogeneic Bone Block Measured by Two Image Matching Tools: Introduction of a Novel Assessment Technique for Graft Resorption
Objective: The purpose of this case report was to present a method for the assessment of volumetric changes of bone blocks during healing and demonstrate its practicability by analysing the resorption of a preshaped allogeneic bone block used for the reconstruction of a complex maxillary defect. Mat...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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University of Zagreb. School of Dental Medicine
2021-01-01
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| Series: | Acta Stomatologica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/388575 |
| _version_ | 1797206870090317824 |
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| author | Oliver Blume Phil Donkiewicz Daniel Palkovics Werner Götz Péter Windisch |
| author_facet | Oliver Blume Phil Donkiewicz Daniel Palkovics Werner Götz Péter Windisch |
| author_sort | Oliver Blume |
| collection | DOAJ |
| description | Objective: The purpose of this case report was to present a method for the assessment of volumetric changes of bone blocks during healing and demonstrate its practicability by analysing the resorption of a preshaped allogeneic bone block used for the reconstruction of a complex maxillary defect. Materials and methods: CBCT-scans of a 19-year-old male treated with an allogeneic bone block were recorded pre-OP, post-OP, and following six months of healing. Graft shrinkage was assessed via two image matching tools, namely coDiagnostiX® and Slicer. A biopsy specimen was harvested along the implant canal at the time of implantation. Results: The osseous defect was successfully restored and advanced graft remodelling was found upon re-entry as confirmed by the histomorphometric and histologic analysis. The initial volumes of the graft determined via coDiagnostiX® and Slicer were 0.373 mL and 0.370 mL., respectively, while graft resorption after six months of healing was 0.011 mL (3.00%) and 0.016 mL (4.33%). Conclusions: The avoidance of bone harvesting and reduction of invasiveness display an important issue in dentoalveolar restorations. However, before grafting materials can be considered a safe alternative, understanding their clinical performance, especially resorption stability, is pivotal. The present case report demonstrates a limited resorption of the allogeneic bone block and further emphasizes the practicability of determining bone resorption by the here introduced method. As our investigation comprises solely one subject, the results should be considered with care and substantiated by further studies. |
| first_indexed | 2024-04-24T09:13:53Z |
| format | Article |
| id | doaj.art-84b7b2804f10461e8e78580d3ddf267f |
| institution | Directory Open Access Journal |
| issn | 0001-7019 1846-0410 |
| language | English |
| last_indexed | 2024-04-24T09:13:53Z |
| publishDate | 2021-01-01 |
| publisher | University of Zagreb. School of Dental Medicine |
| record_format | Article |
| series | Acta Stomatologica Croatica |
| spelling | doaj.art-84b7b2804f10461e8e78580d3ddf267f2024-04-15T17:23:07ZengUniversity of Zagreb. School of Dental MedicineActa Stomatologica Croatica0001-70191846-04102021-01-0155440641710.15644/asc55/4/8Volumetric Changes of a Customized Allogeneic Bone Block Measured by Two Image Matching Tools: Introduction of a Novel Assessment Technique for Graft ResorptionOliver Blume0Phil Donkiewicz1Daniel Palkovics2Werner Götz3Péter Windisch4Private Practice ‘Dres. Back & Blume’, Tal 13, 80331 Munich, GermanyDepartment of Oral Surgery and Dental Emergency Care, Faculty of Health, School of Dentistry, Witten / Herdecke University, North Rhine-Westphalia, GermanyDepartment of Periodontology, Semmelweis University, Szentkirályi u. 47, 1088 Budapest, HungaryDepartment of Orthodontics, Laboratory for Basic Research in Oral Biology, University of Bonn, GermanyDepartment of Periodontology, Semmelweis University, Szentkirályi u. 47, 1088 Budapest, HungaryObjective: The purpose of this case report was to present a method for the assessment of volumetric changes of bone blocks during healing and demonstrate its practicability by analysing the resorption of a preshaped allogeneic bone block used for the reconstruction of a complex maxillary defect. Materials and methods: CBCT-scans of a 19-year-old male treated with an allogeneic bone block were recorded pre-OP, post-OP, and following six months of healing. Graft shrinkage was assessed via two image matching tools, namely coDiagnostiX® and Slicer. A biopsy specimen was harvested along the implant canal at the time of implantation. Results: The osseous defect was successfully restored and advanced graft remodelling was found upon re-entry as confirmed by the histomorphometric and histologic analysis. The initial volumes of the graft determined via coDiagnostiX® and Slicer were 0.373 mL and 0.370 mL., respectively, while graft resorption after six months of healing was 0.011 mL (3.00%) and 0.016 mL (4.33%). Conclusions: The avoidance of bone harvesting and reduction of invasiveness display an important issue in dentoalveolar restorations. However, before grafting materials can be considered a safe alternative, understanding their clinical performance, especially resorption stability, is pivotal. The present case report demonstrates a limited resorption of the allogeneic bone block and further emphasizes the practicability of determining bone resorption by the here introduced method. As our investigation comprises solely one subject, the results should be considered with care and substantiated by further studies.https://hrcak.srce.hr/file/388575MeSH terms: Bone TransplantationAllograftsBone Substitutes Author keywords: Allogeneic Bone GraftBone BlockGraft ResorptionBiomaterials |
| spellingShingle | Oliver Blume Phil Donkiewicz Daniel Palkovics Werner Götz Péter Windisch Volumetric Changes of a Customized Allogeneic Bone Block Measured by Two Image Matching Tools: Introduction of a Novel Assessment Technique for Graft Resorption Acta Stomatologica Croatica MeSH terms: Bone Transplantation Allografts Bone Substitutes Author keywords: Allogeneic Bone Graft Bone Block Graft Resorption Biomaterials |
| title | Volumetric Changes of a Customized Allogeneic Bone Block Measured by Two Image Matching Tools: Introduction of a Novel Assessment Technique for Graft Resorption |
| title_full | Volumetric Changes of a Customized Allogeneic Bone Block Measured by Two Image Matching Tools: Introduction of a Novel Assessment Technique for Graft Resorption |
| title_fullStr | Volumetric Changes of a Customized Allogeneic Bone Block Measured by Two Image Matching Tools: Introduction of a Novel Assessment Technique for Graft Resorption |
| title_full_unstemmed | Volumetric Changes of a Customized Allogeneic Bone Block Measured by Two Image Matching Tools: Introduction of a Novel Assessment Technique for Graft Resorption |
| title_short | Volumetric Changes of a Customized Allogeneic Bone Block Measured by Two Image Matching Tools: Introduction of a Novel Assessment Technique for Graft Resorption |
| title_sort | volumetric changes of a customized allogeneic bone block measured by two image matching tools introduction of a novel assessment technique for graft resorption |
| topic | MeSH terms: Bone Transplantation Allografts Bone Substitutes Author keywords: Allogeneic Bone Graft Bone Block Graft Resorption Biomaterials |
| url | https://hrcak.srce.hr/file/388575 |
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