Excessive rDNA Transcription Drives the Disruption in Nuclear Homeostasis during Entry into Senescence in Budding Yeast
Summary: Budding yeast cells undergo a limited number of divisions before they enter senescence and die. Despite recent mechanistic advances, whether and how molecular events are temporally and causally linked during the transition to senescence remain elusive. Here, using real-time observation of t...
Main Authors: | Sandrine Morlot, Jia Song, Isabelle Léger-Silvestre, Audrey Matifas, Olivier Gadal, Gilles Charvin |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-07-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124719307983 |
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