Prophylactic effect of negative‐pressure wound therapy and delayed sutures against incisional‐surgical site infection after emergency laparotomy for colorectal perforation: A multicenter retrospective cohort study
Abstract Aim The prophylactic effect of negative‐pressure wound therapy against incisional surgical site infection after highly contaminated laparotomies has not been sufficiently explored. This study aimed to evaluate the prophylactic effect of negative‐pressure wound therapy against incisional sur...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-05-01
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| Series: | Annals of Gastroenterological Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ags3.12643 |
| _version_ | 1797834676778303488 |
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| author | Keita Nakatsutsumi Akira Endo Hiroshi Asano Shoichi Shinohara Ryo Kurosaki Shuji Kawashima Wataru Ishii Masashi Nozawa Nobumi Tagaya Yasuhiro Otomo |
| author_facet | Keita Nakatsutsumi Akira Endo Hiroshi Asano Shoichi Shinohara Ryo Kurosaki Shuji Kawashima Wataru Ishii Masashi Nozawa Nobumi Tagaya Yasuhiro Otomo |
| author_sort | Keita Nakatsutsumi |
| collection | DOAJ |
| description | Abstract Aim The prophylactic effect of negative‐pressure wound therapy against incisional surgical site infection after highly contaminated laparotomies has not been sufficiently explored. This study aimed to evaluate the prophylactic effect of negative‐pressure wound therapy against incisional surgical site infection after emergency surgery for colorectal perforation. Methods This nationwide, multicenter, retrospective cohort study analyzed data from the 48 emergency hospitals certificated by the Japanese Society for Abdominal Emergency Medicine. Patients who underwent an emergency laparotomy for colorectal perforation between April 2015 and March 2020 were included in this study. Outcomes, including the incidence of incisional surgical site infection, were compared between patients who were treated with prophylactic negative‐pressure wound therapy and delayed sutures (i.e., negative‐pressure wound therapy group) and patients who were treated with regular wound management (i.e., control group) using 1:4 propensity score matching analysis. Results The negative‐pressure wound therapy group comprised 88 patients, whereas the control group consisted of 1535 patients. Of them, 82 propensity score‐matched pairs (negative‐pressure wound therapy group: 82; control group: 328) were evaluated. The negative‐pressure wound therapy group showed a lower incidence of incisional surgical site infection [18 (22.0%) in the negative‐pressure wound therapy group and 115 (35.0%) in the control group, odds ratio, 0.52; 95% confidence interval, 0.30 to 0.92; p = 0.026]. Conclusions The prophylactic use of negative‐pressure wound therapy with delayed sutures was associated with a lower incidence of incisional surgical site infection after emergency surgery for colorectal perforation. |
| first_indexed | 2024-04-09T14:41:21Z |
| format | Article |
| id | doaj.art-84bdd53d1f2740fcb918b6a5f4dba2fd |
| institution | Directory Open Access Journal |
| issn | 2475-0328 |
| language | English |
| last_indexed | 2024-04-09T14:41:21Z |
| publishDate | 2023-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Annals of Gastroenterological Surgery |
| spelling | doaj.art-84bdd53d1f2740fcb918b6a5f4dba2fd2023-05-03T06:15:53ZengWileyAnnals of Gastroenterological Surgery2475-03282023-05-017344144910.1002/ags3.12643Prophylactic effect of negative‐pressure wound therapy and delayed sutures against incisional‐surgical site infection after emergency laparotomy for colorectal perforation: A multicenter retrospective cohort studyKeita Nakatsutsumi0Akira Endo1Hiroshi Asano2Shoichi Shinohara3Ryo Kurosaki4Shuji Kawashima5Wataru Ishii6Masashi Nozawa7Nobumi Tagaya8Yasuhiro Otomo9Trauma and Acute Critical Care Center Tokyo Medical and Dental University Hospital Tokyo JapanTrauma and Acute Critical Care Center Tokyo Medical and Dental University Hospital Tokyo JapanDepartment of General Surgery Saitama Medical University Saitama JapanDepartment of Surgery, Division of Gastroenterological, General and Transplant Surgery Jichi Medical University Tochigi JapanSurgery Department Japanese Red Cross Maebashi Hospital Maebashi JapanDepartment of Emergency and Critical Care Medicine Wakayama Medical University Wakayama JapanDepartment of Emergency Medicine Japanese Red Cross Society Kyoto Daini Hospital Kyoto JapanDepartment of Surgery Shimada General Medical Center Shizuoka JapanDepartment of Surgery Itabashi Chuo Medical Center Tokyo JapanTrauma and Acute Critical Care Center Tokyo Medical and Dental University Hospital Tokyo JapanAbstract Aim The prophylactic effect of negative‐pressure wound therapy against incisional surgical site infection after highly contaminated laparotomies has not been sufficiently explored. This study aimed to evaluate the prophylactic effect of negative‐pressure wound therapy against incisional surgical site infection after emergency surgery for colorectal perforation. Methods This nationwide, multicenter, retrospective cohort study analyzed data from the 48 emergency hospitals certificated by the Japanese Society for Abdominal Emergency Medicine. Patients who underwent an emergency laparotomy for colorectal perforation between April 2015 and March 2020 were included in this study. Outcomes, including the incidence of incisional surgical site infection, were compared between patients who were treated with prophylactic negative‐pressure wound therapy and delayed sutures (i.e., negative‐pressure wound therapy group) and patients who were treated with regular wound management (i.e., control group) using 1:4 propensity score matching analysis. Results The negative‐pressure wound therapy group comprised 88 patients, whereas the control group consisted of 1535 patients. Of them, 82 propensity score‐matched pairs (negative‐pressure wound therapy group: 82; control group: 328) were evaluated. The negative‐pressure wound therapy group showed a lower incidence of incisional surgical site infection [18 (22.0%) in the negative‐pressure wound therapy group and 115 (35.0%) in the control group, odds ratio, 0.52; 95% confidence interval, 0.30 to 0.92; p = 0.026]. Conclusions The prophylactic use of negative‐pressure wound therapy with delayed sutures was associated with a lower incidence of incisional surgical site infection after emergency surgery for colorectal perforation.https://doi.org/10.1002/ags3.12643colorectal perforationemergency surgeryincisional‐surgical site infectionnegative‐pressure wound therapyprophylactic treatment |
| spellingShingle | Keita Nakatsutsumi Akira Endo Hiroshi Asano Shoichi Shinohara Ryo Kurosaki Shuji Kawashima Wataru Ishii Masashi Nozawa Nobumi Tagaya Yasuhiro Otomo Prophylactic effect of negative‐pressure wound therapy and delayed sutures against incisional‐surgical site infection after emergency laparotomy for colorectal perforation: A multicenter retrospective cohort study Annals of Gastroenterological Surgery colorectal perforation emergency surgery incisional‐surgical site infection negative‐pressure wound therapy prophylactic treatment |
| title | Prophylactic effect of negative‐pressure wound therapy and delayed sutures against incisional‐surgical site infection after emergency laparotomy for colorectal perforation: A multicenter retrospective cohort study |
| title_full | Prophylactic effect of negative‐pressure wound therapy and delayed sutures against incisional‐surgical site infection after emergency laparotomy for colorectal perforation: A multicenter retrospective cohort study |
| title_fullStr | Prophylactic effect of negative‐pressure wound therapy and delayed sutures against incisional‐surgical site infection after emergency laparotomy for colorectal perforation: A multicenter retrospective cohort study |
| title_full_unstemmed | Prophylactic effect of negative‐pressure wound therapy and delayed sutures against incisional‐surgical site infection after emergency laparotomy for colorectal perforation: A multicenter retrospective cohort study |
| title_short | Prophylactic effect of negative‐pressure wound therapy and delayed sutures against incisional‐surgical site infection after emergency laparotomy for colorectal perforation: A multicenter retrospective cohort study |
| title_sort | prophylactic effect of negative pressure wound therapy and delayed sutures against incisional surgical site infection after emergency laparotomy for colorectal perforation a multicenter retrospective cohort study |
| topic | colorectal perforation emergency surgery incisional‐surgical site infection negative‐pressure wound therapy prophylactic treatment |
| url | https://doi.org/10.1002/ags3.12643 |
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