Stimulating at the right time to recover network states in a model of the cortico-basal ganglia-thalamic circuit.
Synchronization of neural oscillations is thought to facilitate communication in the brain. Neurodegenerative pathologies such as Parkinson's disease (PD) can result in synaptic reorganization of the motor circuit, leading to altered neuronal dynamics and impaired neural communication. Treatmen...
Main Authors: | Timothy O West, Peter J Magill, Andrew Sharott, Vladimir Litvak, Simon F Farmer, Hayriye Cagnan |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-03-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1009887 |
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