The Effect of Ultrasound Waves on Melanoma Cells in Presence of Gold Nanoparticles

- Background: Biological effects of ultrasound waves and their applications in the presence of nanoparticles are a rapidly growing research area. In recent years, ultrasonic therapy of cancer cells has been developed successfully. In this study, effects of ultrasound waves in the presence of gold na...

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Main Authors: Ahmad Shanei, Milad Baradaran, Mohammad Mahdi Shanei
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2017-02-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/7199
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author Ahmad Shanei
Milad Baradaran
Mohammad Mahdi Shanei
author_facet Ahmad Shanei
Milad Baradaran
Mohammad Mahdi Shanei
author_sort Ahmad Shanei
collection DOAJ
description - Background: Biological effects of ultrasound waves and their applications in the presence of nanoparticles are a rapidly growing research area. In recent years, ultrasonic therapy of cancer cells has been developed successfully. In this study, effects of ultrasound waves in the presence of gold nanoparticles on the melanoma cells were evaluated. Methods: The Melanoma cells were cultured and divided into 4 groups of control, gold nanoparticle, ultrasound alone and ultrasound waves at the presence of gold nanoparticle. Ultrasound irradiation at intensity of 2 W/cm2 was performed on the cells for 3 minutes. Findings: There was a significant difference in the percent of cell viability between the ultrasound + gold nanoparticles and the other groups. In addition, there was a significant difference between the ultrasound and the control groups, too. Conclusion: Results of this study reveal that ultrasound in the presence of gold nanoparticles can be efficiently used for treatment of melanoma cells; as gold nanoparticles act as cavitation nuclei.
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spelling doaj.art-84c48fd900cb40ed99c8a1148187832f2023-09-03T00:20:02ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2017-02-0134412155015552398The Effect of Ultrasound Waves on Melanoma Cells in Presence of Gold NanoparticlesAhmad Shanei0Milad Baradaran1Mohammad Mahdi Shanei2Associated Professor, Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranPhD Student, Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranPhD Student, Department of Nano Materials, School of Materials Engineering, Tarbiat Modares University, Tehran, Iran- Background: Biological effects of ultrasound waves and their applications in the presence of nanoparticles are a rapidly growing research area. In recent years, ultrasonic therapy of cancer cells has been developed successfully. In this study, effects of ultrasound waves in the presence of gold nanoparticles on the melanoma cells were evaluated. Methods: The Melanoma cells were cultured and divided into 4 groups of control, gold nanoparticle, ultrasound alone and ultrasound waves at the presence of gold nanoparticle. Ultrasound irradiation at intensity of 2 W/cm2 was performed on the cells for 3 minutes. Findings: There was a significant difference in the percent of cell viability between the ultrasound + gold nanoparticles and the other groups. In addition, there was a significant difference between the ultrasound and the control groups, too. Conclusion: Results of this study reveal that ultrasound in the presence of gold nanoparticles can be efficiently used for treatment of melanoma cells; as gold nanoparticles act as cavitation nuclei.http://jims.mui.ac.ir/index.php/jims/article/view/7199Gold nanoparticlesUltrasound wavesCavitationMelanoma cell
spellingShingle Ahmad Shanei
Milad Baradaran
Mohammad Mahdi Shanei
The Effect of Ultrasound Waves on Melanoma Cells in Presence of Gold Nanoparticles
مجله دانشکده پزشکی اصفهان
Gold nanoparticles
Ultrasound waves
Cavitation
Melanoma cell
title The Effect of Ultrasound Waves on Melanoma Cells in Presence of Gold Nanoparticles
title_full The Effect of Ultrasound Waves on Melanoma Cells in Presence of Gold Nanoparticles
title_fullStr The Effect of Ultrasound Waves on Melanoma Cells in Presence of Gold Nanoparticles
title_full_unstemmed The Effect of Ultrasound Waves on Melanoma Cells in Presence of Gold Nanoparticles
title_short The Effect of Ultrasound Waves on Melanoma Cells in Presence of Gold Nanoparticles
title_sort effect of ultrasound waves on melanoma cells in presence of gold nanoparticles
topic Gold nanoparticles
Ultrasound waves
Cavitation
Melanoma cell
url http://jims.mui.ac.ir/index.php/jims/article/view/7199
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