Design, Synthesis, Characterization, and Evaluation of the Anti-HT-29 Colorectal Cell Line Activity of Novel 8-Oxyquinolinate-Platinum(II)-Loaded Nanostructured Lipid Carriers Targeted with Riboflavin

Design, Synthesis, Characterization, and Evaluation of the Anti-HT-29 Colorectal Cell Line Activity of Novel 8-Oxyquinolinate-Platinum(II)-Loaded Nanostructured Lipid Carriers Targeted with Riboflavin

Colorectal cancer is occasionally called colon or rectal cancer, depending on where cancer begins to form, and is the second leading cause of cancer death among both men and women. The platinum-based [PtCl(8-O-quinolinate)(dmso)] (8-QO-Pt) compound has demonstrated encouraging anticancer activity. T...

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Bibliographic Details
Main Authors: Tugce Boztepe, Sebastián Scioli-Montoto, Rocio C. Gambaro, María Esperanza Ruiz, Silvia Cabrera, José Alemán, Germán A. Islan, Guillermo R. Castro, Ignacio E. León
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pharmaceutics
Subjects:
drug delivery
colorectal cancer
platinum
riboflavin
Online Access:https://www.mdpi.com/1999-4923/15/3/1021

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