Carbon-based smart nanomaterials in biomedicine and neuroengineering

The search for advanced biomimetic materials that are capable of offering a scaffold for biological tissues during regeneration or of electrically connecting artificial devices with cellular structures to restore damaged brain functions is at the forefront of interdisciplinary research in materials...

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Main Authors: Antonina M. Monaco, Michele Giugliano
Format: Article
Language:English
Published: Beilstein-Institut 2014-10-01
Series:Beilstein Journal of Nanotechnology
Subjects:
Online Access:https://doi.org/10.3762/bjnano.5.196
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author Antonina M. Monaco
Michele Giugliano
author_facet Antonina M. Monaco
Michele Giugliano
author_sort Antonina M. Monaco
collection DOAJ
description The search for advanced biomimetic materials that are capable of offering a scaffold for biological tissues during regeneration or of electrically connecting artificial devices with cellular structures to restore damaged brain functions is at the forefront of interdisciplinary research in materials science. Bioactive nanoparticles for drug delivery, substrates for nerve regeneration and active guidance, as well as supramolecular architectures mimicking the extracellular environment to reduce inflammatory responses in brain implants, are within reach thanks to the advancements in nanotechnology. In particular, carbon-based nanostructured materials, such as graphene, carbon nanotubes (CNTs) and nanodiamonds (NDs), have demonstrated to be highly promising materials for designing and fabricating nanoelectrodes and substrates for cell growth, by virtue of their peerless optical, electrical, thermal, and mechanical properties. In this review we discuss the state-of-the-art in the applications of nanomaterials in biological and biomedical fields, with a particular emphasis on neuroengineering.
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spelling doaj.art-84d15cf288954292b313458af32ba6622022-12-21T19:36:45ZengBeilstein-InstitutBeilstein Journal of Nanotechnology2190-42862014-10-01511849186310.3762/bjnano.5.1962190-4286-5-196Carbon-based smart nanomaterials in biomedicine and neuroengineeringAntonina M. Monaco0Michele Giugliano1Theoretical Neurobiology and Neuroengineering Lab, Department of Biomedical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Wilrijk, BelgiumTheoretical Neurobiology and Neuroengineering Lab, Department of Biomedical Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Wilrijk, BelgiumThe search for advanced biomimetic materials that are capable of offering a scaffold for biological tissues during regeneration or of electrically connecting artificial devices with cellular structures to restore damaged brain functions is at the forefront of interdisciplinary research in materials science. Bioactive nanoparticles for drug delivery, substrates for nerve regeneration and active guidance, as well as supramolecular architectures mimicking the extracellular environment to reduce inflammatory responses in brain implants, are within reach thanks to the advancements in nanotechnology. In particular, carbon-based nanostructured materials, such as graphene, carbon nanotubes (CNTs) and nanodiamonds (NDs), have demonstrated to be highly promising materials for designing and fabricating nanoelectrodes and substrates for cell growth, by virtue of their peerless optical, electrical, thermal, and mechanical properties. In this review we discuss the state-of-the-art in the applications of nanomaterials in biological and biomedical fields, with a particular emphasis on neuroengineering.https://doi.org/10.3762/bjnano.5.196carbon nanotubeselectrophysiologygraphenemicroelectrodesnanodiamondsnanotechnologyneuroengineeringneuronal culturesneuroscience
spellingShingle Antonina M. Monaco
Michele Giugliano
Carbon-based smart nanomaterials in biomedicine and neuroengineering
Beilstein Journal of Nanotechnology
carbon nanotubes
electrophysiology
graphene
microelectrodes
nanodiamonds
nanotechnology
neuroengineering
neuronal cultures
neuroscience
title Carbon-based smart nanomaterials in biomedicine and neuroengineering
title_full Carbon-based smart nanomaterials in biomedicine and neuroengineering
title_fullStr Carbon-based smart nanomaterials in biomedicine and neuroengineering
title_full_unstemmed Carbon-based smart nanomaterials in biomedicine and neuroengineering
title_short Carbon-based smart nanomaterials in biomedicine and neuroengineering
title_sort carbon based smart nanomaterials in biomedicine and neuroengineering
topic carbon nanotubes
electrophysiology
graphene
microelectrodes
nanodiamonds
nanotechnology
neuroengineering
neuronal cultures
neuroscience
url https://doi.org/10.3762/bjnano.5.196
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