Human Papilloma Virus and Esophageal Squamous Cell Carcinoma
Human papilloma virus (HPV) has been suggested as an etiology of esophageal squamous cell carcinoma (SCC). The aim of this study was to investigate the prevalence of HPV infection in esophageal SCCs in our region with strict contamination control to prevent false positive results. Thirty cases of es...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2013-04-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | http://acta.tums.ac.ir/index.php/acta/article/view/4683/4305 |
| _version_ | 1818281732920573952 |
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| author | Hayedeh Haeri Omid Mardany Fahimeh Asadi-Amoli Reza Shahsiah |
| author_facet | Hayedeh Haeri Omid Mardany Fahimeh Asadi-Amoli Reza Shahsiah |
| author_sort | Hayedeh Haeri |
| collection | DOAJ |
| description | Human papilloma virus (HPV) has been suggested as an etiology of esophageal squamous cell carcinoma (SCC). The aim of this study was to investigate the prevalence of HPV infection in esophageal SCCs in our region with strict contamination control to prevent false positive results. Thirty cases of esophageal squamous cell carcinomas were chosen by simple random selection in a period of two years. PCR for target sequence of HPV L1 gene was performed on nucleic acid extracted from samples by means of GP5+/GP6+ primers. All tissue samples in both case and control groups were negative for HPV-DNA. Although the number of cases in this study was limited, the contribution of HPV in substantial number of esophageal SCCs in our region is unlikely. |
| first_indexed | 2024-12-13T00:09:48Z |
| format | Article |
| id | doaj.art-84d1cdfc630c4da1be7a82ba409a0542 |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-12-13T00:09:48Z |
| publishDate | 2013-04-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-84d1cdfc630c4da1be7a82ba409a05422022-12-22T00:06:02ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942013-04-01514242245Human Papilloma Virus and Esophageal Squamous Cell CarcinomaHayedeh HaeriOmid MardanyFahimeh Asadi-AmoliReza ShahsiahHuman papilloma virus (HPV) has been suggested as an etiology of esophageal squamous cell carcinoma (SCC). The aim of this study was to investigate the prevalence of HPV infection in esophageal SCCs in our region with strict contamination control to prevent false positive results. Thirty cases of esophageal squamous cell carcinomas were chosen by simple random selection in a period of two years. PCR for target sequence of HPV L1 gene was performed on nucleic acid extracted from samples by means of GP5+/GP6+ primers. All tissue samples in both case and control groups were negative for HPV-DNA. Although the number of cases in this study was limited, the contribution of HPV in substantial number of esophageal SCCs in our region is unlikely.http://acta.tums.ac.ir/index.php/acta/article/view/4683/4305Human Papilloma VirusPolymerase Chain ReactionSquamous Cell Carcinoma |
| spellingShingle | Hayedeh Haeri Omid Mardany Fahimeh Asadi-Amoli Reza Shahsiah Human Papilloma Virus and Esophageal Squamous Cell Carcinoma Acta Medica Iranica Human Papilloma Virus Polymerase Chain Reaction Squamous Cell Carcinoma |
| title | Human Papilloma Virus and Esophageal Squamous Cell Carcinoma |
| title_full | Human Papilloma Virus and Esophageal Squamous Cell Carcinoma |
| title_fullStr | Human Papilloma Virus and Esophageal Squamous Cell Carcinoma |
| title_full_unstemmed | Human Papilloma Virus and Esophageal Squamous Cell Carcinoma |
| title_short | Human Papilloma Virus and Esophageal Squamous Cell Carcinoma |
| title_sort | human papilloma virus and esophageal squamous cell carcinoma |
| topic | Human Papilloma Virus Polymerase Chain Reaction Squamous Cell Carcinoma |
| url | http://acta.tums.ac.ir/index.php/acta/article/view/4683/4305 |
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