The effect of a short, animated story-based video on COVID-19 vaccine hesitancy: A study protocol for an online randomized controlled trial

IntroductionExposure to a high volume of vaccine misinformation on social media can have a negative effect on vaccine confidence and rates. To counteract misinformation, we designed a collage of three short, animated story-based (SAS) videos to convey scientifically informed and accessible informati...

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Main Authors: Sandra Barteit, Violetta Hachaturyan, Ferdinand Beleites, Tilman Kühn, Caterina Favaretti, Maya Adam, Till Bärnighausen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Public Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2022.939227/full
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author Sandra Barteit
Violetta Hachaturyan
Ferdinand Beleites
Tilman Kühn
Tilman Kühn
Caterina Favaretti
Caterina Favaretti
Maya Adam
Till Bärnighausen
Till Bärnighausen
Till Bärnighausen
author_facet Sandra Barteit
Violetta Hachaturyan
Ferdinand Beleites
Tilman Kühn
Tilman Kühn
Caterina Favaretti
Caterina Favaretti
Maya Adam
Till Bärnighausen
Till Bärnighausen
Till Bärnighausen
author_sort Sandra Barteit
collection DOAJ
description IntroductionExposure to a high volume of vaccine misinformation on social media can have a negative effect on vaccine confidence and rates. To counteract misinformation, we designed a collage of three short, animated story-based (SAS) videos to convey scientifically informed and accessible information about COVID-19 vaccine applicable to a social media context.Methods and analysisWe will conduct an online randomized controlled trial primarily to: (1) determine the effectiveness of SAS videos in improving COVID-19 vaccine knowledge; (2) evaluate the effectiveness of SAS videos in increasing behavioral intent for COVID-19 vaccination; and (3) quantify people's interest in watching SAS videos about the COVID-19 vaccine. We also aim to identify barriers and facilitators to COIVD-19 vaccinations that have been shown to minimize vaccine hesitancy between vaccinated and unvaccinated populations. Using a web-based recruitment platform, a total of 10,000 adults from the United States will be recruited and randomly assigned to (1) a SAS video collage arm, (2) an attention placebo control video arm, or (3) no intervention arm (1:1:1). Furthermore, we will measure behavioral intent to obtain information on vaccination regarding COVID-19. At the end of the trial, participants randomized to arm 2 and arm 3 will be given the option of watching one of the intervention videos voluntarily to assess participant engagement with SAS videos. Finally, we will assess individual factors associated with vaccine hesitancy - hope, optimism, COVID-19 perceived risks and benefits, self-efficacy, perceived social norms, and trust - and compare vaccinated and unvaccinated participants across the three arms.DiscussionsEvidence-based information from official channels can be complex and inaccessible to the general public, whereas false information on social media is frequently shared in brief postings, images, or videos that can easily reach the general public, thereby rapidly disseminating (mis-)information. To avoid the spread of misinformation, social media may be used to deliver evidence-based and emotionally compelling information in a readily accessible format in order to pre-empt misinformation. Our findings may help inform future SAS efforts addressing COVID-19 and other important public health challenges.Ethics and disseminationThe study was approved by the Heidelberg University Hospital's Ethics Committee (S-163/2022). The trial was registered with German Clinical Trials Register (www.drks.de) on 5 January 2022: number DRKS00027938. Findings of the study will be published in peer-reviewed scientific publications and possibly presented at scientific conferences.
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spelling doaj.art-84d45d8007fc4120a35404efd8a5e2d82022-12-22T04:02:36ZengFrontiers Media S.A.Frontiers in Public Health2296-25652022-08-011010.3389/fpubh.2022.939227939227The effect of a short, animated story-based video on COVID-19 vaccine hesitancy: A study protocol for an online randomized controlled trialSandra Barteit0Violetta Hachaturyan1Ferdinand Beleites2Tilman Kühn3Tilman Kühn4Caterina Favaretti5Caterina Favaretti6Maya Adam7Till Bärnighausen8Till Bärnighausen9Till Bärnighausen10Heidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, GermanyHeidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, GermanyHeidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, GermanyHeidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, GermanyInstitute for Global Food Security (IGFS), Queen's University Belfast, Belfast, United KingdomHeidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, GermanyProfessorship of Behavioral Science for Disease Prevention and Health Care, Technical University of Munich, Munich, GermanyDepartment of Pediatrics, Stanford University School of Medicine, Stanford, CA, United StatesHeidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, GermanyAfrica Health Research Institute (AHRI), Durban, South AfricaHarvard Center for Population and Development Studies, Cambridge, MA, United StatesIntroductionExposure to a high volume of vaccine misinformation on social media can have a negative effect on vaccine confidence and rates. To counteract misinformation, we designed a collage of three short, animated story-based (SAS) videos to convey scientifically informed and accessible information about COVID-19 vaccine applicable to a social media context.Methods and analysisWe will conduct an online randomized controlled trial primarily to: (1) determine the effectiveness of SAS videos in improving COVID-19 vaccine knowledge; (2) evaluate the effectiveness of SAS videos in increasing behavioral intent for COVID-19 vaccination; and (3) quantify people's interest in watching SAS videos about the COVID-19 vaccine. We also aim to identify barriers and facilitators to COIVD-19 vaccinations that have been shown to minimize vaccine hesitancy between vaccinated and unvaccinated populations. Using a web-based recruitment platform, a total of 10,000 adults from the United States will be recruited and randomly assigned to (1) a SAS video collage arm, (2) an attention placebo control video arm, or (3) no intervention arm (1:1:1). Furthermore, we will measure behavioral intent to obtain information on vaccination regarding COVID-19. At the end of the trial, participants randomized to arm 2 and arm 3 will be given the option of watching one of the intervention videos voluntarily to assess participant engagement with SAS videos. Finally, we will assess individual factors associated with vaccine hesitancy - hope, optimism, COVID-19 perceived risks and benefits, self-efficacy, perceived social norms, and trust - and compare vaccinated and unvaccinated participants across the three arms.DiscussionsEvidence-based information from official channels can be complex and inaccessible to the general public, whereas false information on social media is frequently shared in brief postings, images, or videos that can easily reach the general public, thereby rapidly disseminating (mis-)information. To avoid the spread of misinformation, social media may be used to deliver evidence-based and emotionally compelling information in a readily accessible format in order to pre-empt misinformation. Our findings may help inform future SAS efforts addressing COVID-19 and other important public health challenges.Ethics and disseminationThe study was approved by the Heidelberg University Hospital's Ethics Committee (S-163/2022). The trial was registered with German Clinical Trials Register (www.drks.de) on 5 January 2022: number DRKS00027938. Findings of the study will be published in peer-reviewed scientific publications and possibly presented at scientific conferences.https://www.frontiersin.org/articles/10.3389/fpubh.2022.939227/fullCOVID-19vaccine hesitancyshort videoanimated videospublic healthrandomized control trial (RCT)
spellingShingle Sandra Barteit
Violetta Hachaturyan
Ferdinand Beleites
Tilman Kühn
Tilman Kühn
Caterina Favaretti
Caterina Favaretti
Maya Adam
Till Bärnighausen
Till Bärnighausen
Till Bärnighausen
The effect of a short, animated story-based video on COVID-19 vaccine hesitancy: A study protocol for an online randomized controlled trial
Frontiers in Public Health
COVID-19
vaccine hesitancy
short video
animated videos
public health
randomized control trial (RCT)
title The effect of a short, animated story-based video on COVID-19 vaccine hesitancy: A study protocol for an online randomized controlled trial
title_full The effect of a short, animated story-based video on COVID-19 vaccine hesitancy: A study protocol for an online randomized controlled trial
title_fullStr The effect of a short, animated story-based video on COVID-19 vaccine hesitancy: A study protocol for an online randomized controlled trial
title_full_unstemmed The effect of a short, animated story-based video on COVID-19 vaccine hesitancy: A study protocol for an online randomized controlled trial
title_short The effect of a short, animated story-based video on COVID-19 vaccine hesitancy: A study protocol for an online randomized controlled trial
title_sort effect of a short animated story based video on covid 19 vaccine hesitancy a study protocol for an online randomized controlled trial
topic COVID-19
vaccine hesitancy
short video
animated videos
public health
randomized control trial (RCT)
url https://www.frontiersin.org/articles/10.3389/fpubh.2022.939227/full
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