CRYOGENIC TREATMENT FOR CANCER OF THE TONGUE AND ORAL CAVITY (ANALYSIS OF ITS EFFICIENCY ACCORDING TO SURVIVAL RATES IN THE PERIOD 1975–2009)

Case histories of 366 patients with cancer of the oral mucosa, tongue, and oropharynx who had received cryogenic treatment at the N.N. Blokhin Russian Cancer Research Center in the period 1975 to 2009 served as the material for the investigation. Analysis of the longterm results of cryogenic treatme...

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Main Author: T. D. Tabolinovskaya
Format: Article
Language:Russian
Published: ABV-press 2015-04-01
Series:Опухоли головы и шеи
Subjects:
Online Access:https://ogsh.abvpress.ru/jour/article/view/10
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author T. D. Tabolinovskaya
author_facet T. D. Tabolinovskaya
author_sort T. D. Tabolinovskaya
collection DOAJ
description Case histories of 366 patients with cancer of the oral mucosa, tongue, and oropharynx who had received cryogenic treatment at the N.N. Blokhin Russian Cancer Research Center in the period 1975 to 2009 served as the material for the investigation. Analysis of the longterm results of cryogenic treatment for primary and recurrent cancers and tumors untreated after traditional treatments showed the efficiency of this method in 75.8 and 48.2 % of primary and recurrent cancer patients, respectively. Five- and ten-year relapse-free survival rates were 73 and 68 %, respectively; and the survival rates after 15 years remained stable and those after 20 years averaged 65 % for all sites of oropharyngeal cancer. Recurrent cancer occurred in 21.4 % of the 303 patients who had completed treatment: in 15.2 % of the patients with primary cancer and in 21.7 % of those with recurrent cancer and untreated tumors. Local complications emerged from the wound in 18.3 % and were arrested in the postoperative period. Cryogenic treatment is recommended for oncological practice; its indications and contraindications were defined.
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spelling doaj.art-84dc17c97073483fb80017defe01fc1a2023-03-13T08:43:16ZrusABV-pressОпухоли головы и шеи2222-14682411-46342015-04-010141610.17650/2222-1468-2013-0-1-4-1610CRYOGENIC TREATMENT FOR CANCER OF THE TONGUE AND ORAL CAVITY (ANALYSIS OF ITS EFFICIENCY ACCORDING TO SURVIVAL RATES IN THE PERIOD 1975–2009)T. D. Tabolinovskaya0ФГБНУ «Российский онкологический научный центр им. Н.Н. Блохина» РАМН, МоскваCase histories of 366 patients with cancer of the oral mucosa, tongue, and oropharynx who had received cryogenic treatment at the N.N. Blokhin Russian Cancer Research Center in the period 1975 to 2009 served as the material for the investigation. Analysis of the longterm results of cryogenic treatment for primary and recurrent cancers and tumors untreated after traditional treatments showed the efficiency of this method in 75.8 and 48.2 % of primary and recurrent cancer patients, respectively. Five- and ten-year relapse-free survival rates were 73 and 68 %, respectively; and the survival rates after 15 years remained stable and those after 20 years averaged 65 % for all sites of oropharyngeal cancer. Recurrent cancer occurred in 21.4 % of the 303 patients who had completed treatment: in 15.2 % of the patients with primary cancer and in 21.7 % of those with recurrent cancer and untreated tumors. Local complications emerged from the wound in 18.3 % and were arrested in the postoperative period. Cryogenic treatment is recommended for oncological practice; its indications and contraindications were defined.https://ogsh.abvpress.ru/jour/article/view/10ракслизистые оболочкиязыкдно полости ртащекаретромолярная областьальвеолярный край челюститвердое неборотоглоткакриохирургияэффективностьрецидивыметастазыпродолжительность жизни
spellingShingle T. D. Tabolinovskaya
CRYOGENIC TREATMENT FOR CANCER OF THE TONGUE AND ORAL CAVITY (ANALYSIS OF ITS EFFICIENCY ACCORDING TO SURVIVAL RATES IN THE PERIOD 1975–2009)
Опухоли головы и шеи
рак
слизистые оболочки
язык
дно полости рта
щека
ретромолярная область
альвеолярный край челюсти
твердое небо
ротоглотка
криохирургия
эффективность
рецидивы
метастазы
продолжительность жизни
title CRYOGENIC TREATMENT FOR CANCER OF THE TONGUE AND ORAL CAVITY (ANALYSIS OF ITS EFFICIENCY ACCORDING TO SURVIVAL RATES IN THE PERIOD 1975–2009)
title_full CRYOGENIC TREATMENT FOR CANCER OF THE TONGUE AND ORAL CAVITY (ANALYSIS OF ITS EFFICIENCY ACCORDING TO SURVIVAL RATES IN THE PERIOD 1975–2009)
title_fullStr CRYOGENIC TREATMENT FOR CANCER OF THE TONGUE AND ORAL CAVITY (ANALYSIS OF ITS EFFICIENCY ACCORDING TO SURVIVAL RATES IN THE PERIOD 1975–2009)
title_full_unstemmed CRYOGENIC TREATMENT FOR CANCER OF THE TONGUE AND ORAL CAVITY (ANALYSIS OF ITS EFFICIENCY ACCORDING TO SURVIVAL RATES IN THE PERIOD 1975–2009)
title_short CRYOGENIC TREATMENT FOR CANCER OF THE TONGUE AND ORAL CAVITY (ANALYSIS OF ITS EFFICIENCY ACCORDING TO SURVIVAL RATES IN THE PERIOD 1975–2009)
title_sort cryogenic treatment for cancer of the tongue and oral cavity analysis of its efficiency according to survival rates in the period 1975 2009
topic рак
слизистые оболочки
язык
дно полости рта
щека
ретромолярная область
альвеолярный край челюсти
твердое небо
ротоглотка
криохирургия
эффективность
рецидивы
метастазы
продолжительность жизни
url https://ogsh.abvpress.ru/jour/article/view/10
work_keys_str_mv AT tdtabolinovskaya cryogenictreatmentforcancerofthetongueandoralcavityanalysisofitsefficiencyaccordingtosurvivalratesintheperiod19752009