Recent advances in the treatment of patients with obesity and chronic kidney disease

AbstractObesity is a chronic disease characterised by excess adiposity, which impairs health. The high prevalence of obesity raises the risk of long-term medical complications including type 2 diabetes and chronic kidney disease. Several studies have focused on patients with obesity, type 2 diabetes...

Full description

Bibliographic Details
Main Authors: Roshaida Abdul Wahab, Ricardo V. Cohen, Carel W. le Roux
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Annals of Medicine
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2023.2203517
_version_ 1797353745666801664
author Roshaida Abdul Wahab
Ricardo V. Cohen
Carel W. le Roux
author_facet Roshaida Abdul Wahab
Ricardo V. Cohen
Carel W. le Roux
author_sort Roshaida Abdul Wahab
collection DOAJ
description AbstractObesity is a chronic disease characterised by excess adiposity, which impairs health. The high prevalence of obesity raises the risk of long-term medical complications including type 2 diabetes and chronic kidney disease. Several studies have focused on patients with obesity, type 2 diabetes and chronic kidney disease due to the increased prevalence of diabetic kidney disease. Several randomized controlled trials on sodium-glucose cotransporter 2 inhibitors, glucagon-like peptide-1 analogues, and bariatric surgery in diabetic kidney disease showed renoprotective effects. However, further research is critical to address the treatment of patients with obesity and chronic kidney disease to lessen morbidity.Key messageObesity is a driver of chronic kidney disease, and type 2 diabetes, along with obesity, accelerates chronic kidney disease.Several randomized controlled trials on sodium-glucose cotransporter 2 inhibitors, glucagon-like peptide-1 analogues, and bariatric surgery in diabetic kidney disease demonstrate the improvement of renal outcomes.There is a need to address the treatment of patients with obesity and CKD to lessen morbidity.
first_indexed 2024-03-08T13:34:26Z
format Article
id doaj.art-84e0734e58cc4cff90f794e283776db7
institution Directory Open Access Journal
issn 0785-3890
1365-2060
language English
last_indexed 2024-03-08T13:34:26Z
publishDate 2023-12-01
publisher Taylor & Francis Group
record_format Article
series Annals of Medicine
spelling doaj.art-84e0734e58cc4cff90f794e283776db72024-01-16T19:13:22ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602023-12-0155110.1080/07853890.2023.2203517Recent advances in the treatment of patients with obesity and chronic kidney diseaseRoshaida Abdul Wahab0Ricardo V. Cohen1Carel W. le Roux2Diabetes Complications Research Centre, University College Dublin, Dublin, IrelandCenter for the Treatment of Obesity and Diabetes, Hospital Oswaldo Cruz, Sao Paulo, BrasilDiabetes Complications Research Centre, University College Dublin, Dublin, IrelandAbstractObesity is a chronic disease characterised by excess adiposity, which impairs health. The high prevalence of obesity raises the risk of long-term medical complications including type 2 diabetes and chronic kidney disease. Several studies have focused on patients with obesity, type 2 diabetes and chronic kidney disease due to the increased prevalence of diabetic kidney disease. Several randomized controlled trials on sodium-glucose cotransporter 2 inhibitors, glucagon-like peptide-1 analogues, and bariatric surgery in diabetic kidney disease showed renoprotective effects. However, further research is critical to address the treatment of patients with obesity and chronic kidney disease to lessen morbidity.Key messageObesity is a driver of chronic kidney disease, and type 2 diabetes, along with obesity, accelerates chronic kidney disease.Several randomized controlled trials on sodium-glucose cotransporter 2 inhibitors, glucagon-like peptide-1 analogues, and bariatric surgery in diabetic kidney disease demonstrate the improvement of renal outcomes.There is a need to address the treatment of patients with obesity and CKD to lessen morbidity.https://www.tandfonline.com/doi/10.1080/07853890.2023.2203517Obesitydiabetic kidney diseasesodium-glucose cotransporter 2 inhibitorsglucagon-like peptide-1 analoguesbariatric surgerychronic kidney disease
spellingShingle Roshaida Abdul Wahab
Ricardo V. Cohen
Carel W. le Roux
Recent advances in the treatment of patients with obesity and chronic kidney disease
Annals of Medicine
Obesity
diabetic kidney disease
sodium-glucose cotransporter 2 inhibitors
glucagon-like peptide-1 analogues
bariatric surgery
chronic kidney disease
title Recent advances in the treatment of patients with obesity and chronic kidney disease
title_full Recent advances in the treatment of patients with obesity and chronic kidney disease
title_fullStr Recent advances in the treatment of patients with obesity and chronic kidney disease
title_full_unstemmed Recent advances in the treatment of patients with obesity and chronic kidney disease
title_short Recent advances in the treatment of patients with obesity and chronic kidney disease
title_sort recent advances in the treatment of patients with obesity and chronic kidney disease
topic Obesity
diabetic kidney disease
sodium-glucose cotransporter 2 inhibitors
glucagon-like peptide-1 analogues
bariatric surgery
chronic kidney disease
url https://www.tandfonline.com/doi/10.1080/07853890.2023.2203517
work_keys_str_mv AT roshaidaabdulwahab recentadvancesinthetreatmentofpatientswithobesityandchronickidneydisease
AT ricardovcohen recentadvancesinthetreatmentofpatientswithobesityandchronickidneydisease
AT carelwleroux recentadvancesinthetreatmentofpatientswithobesityandchronickidneydisease