Cytological evaluation of pericardial fluids: A 5 years experience in tertiary care center

Background: Cytological examination of pericardial effusion fluids is important in diagnosing the etiology of underlying disease, staging, and prognosis of cancer. Aims and Objectives: (1) To study cytological evaluation of pericardial effusions in various pathological conditions in a tertiary care...

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Main Authors: Surekha Yadav, Meeta Singh, Pomilla Singh, Sharmana Mandal, Nita Khurana, Shyam Lata Jain
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2019;volume=62;issue=2;spage=270;epage=273;aulast=Yadav
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author Surekha Yadav
Meeta Singh
Pomilla Singh
Sharmana Mandal
Nita Khurana
Shyam Lata Jain
author_facet Surekha Yadav
Meeta Singh
Pomilla Singh
Sharmana Mandal
Nita Khurana
Shyam Lata Jain
author_sort Surekha Yadav
collection DOAJ
description Background: Cytological examination of pericardial effusion fluids is important in diagnosing the etiology of underlying disease, staging, and prognosis of cancer. Aims and Objectives: (1) To study cytological evaluation of pericardial effusions in various pathological conditions in a tertiary care center. (2) To analyze their frequency and clincopathological correlation of the diagnosis. Materials and Methods: Our study was a retrospective study performed in the Department of Pathology from 1st January 2012 to 31st December 2016. The study sample included all the pericardial effusions submitted in the pathology department for cytological evaluation. Clinical details and relevant parameters correlated with clinical findings. Each fluid underwent cytospin and cytocentrifuge along with preparation of conventional smears. Results: Of 120 cases, 80% were of benign effusion and 20% were of malignant effusion. Male-to-female ratio was 1.44:1 with patient age ranging from 3 to 90 years. Conclusion: Benign effusions can been seen in younger age group and malignant ones in the older age group. The preliminary pericardial fluid analysis in resource-limited settings is the most convenient and cost-effective method for accurate diagnosis. It reduces the demand of invasive investigations and its complications. At times, it is the first test to point toward underlying malignant process thereby affecting the prognosis, survival, and treatment outcome of the patient.
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spelling doaj.art-84e2ae2da69645e186aedd03ef0255ef2022-12-22T00:22:02ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292019-01-0162227027310.4103/IJPM.IJPM_360_18Cytological evaluation of pericardial fluids: A 5 years experience in tertiary care centerSurekha YadavMeeta SinghPomilla SinghSharmana MandalNita KhuranaShyam Lata JainBackground: Cytological examination of pericardial effusion fluids is important in diagnosing the etiology of underlying disease, staging, and prognosis of cancer. Aims and Objectives: (1) To study cytological evaluation of pericardial effusions in various pathological conditions in a tertiary care center. (2) To analyze their frequency and clincopathological correlation of the diagnosis. Materials and Methods: Our study was a retrospective study performed in the Department of Pathology from 1st January 2012 to 31st December 2016. The study sample included all the pericardial effusions submitted in the pathology department for cytological evaluation. Clinical details and relevant parameters correlated with clinical findings. Each fluid underwent cytospin and cytocentrifuge along with preparation of conventional smears. Results: Of 120 cases, 80% were of benign effusion and 20% were of malignant effusion. Male-to-female ratio was 1.44:1 with patient age ranging from 3 to 90 years. Conclusion: Benign effusions can been seen in younger age group and malignant ones in the older age group. The preliminary pericardial fluid analysis in resource-limited settings is the most convenient and cost-effective method for accurate diagnosis. It reduces the demand of invasive investigations and its complications. At times, it is the first test to point toward underlying malignant process thereby affecting the prognosis, survival, and treatment outcome of the patient.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2019;volume=62;issue=2;spage=270;epage=273;aulast=YadavLymphomapericardial effusionpericarditistuberculosis
spellingShingle Surekha Yadav
Meeta Singh
Pomilla Singh
Sharmana Mandal
Nita Khurana
Shyam Lata Jain
Cytological evaluation of pericardial fluids: A 5 years experience in tertiary care center
Indian Journal of Pathology and Microbiology
Lymphoma
pericardial effusion
pericarditis
tuberculosis
title Cytological evaluation of pericardial fluids: A 5 years experience in tertiary care center
title_full Cytological evaluation of pericardial fluids: A 5 years experience in tertiary care center
title_fullStr Cytological evaluation of pericardial fluids: A 5 years experience in tertiary care center
title_full_unstemmed Cytological evaluation of pericardial fluids: A 5 years experience in tertiary care center
title_short Cytological evaluation of pericardial fluids: A 5 years experience in tertiary care center
title_sort cytological evaluation of pericardial fluids a 5 years experience in tertiary care center
topic Lymphoma
pericardial effusion
pericarditis
tuberculosis
url http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2019;volume=62;issue=2;spage=270;epage=273;aulast=Yadav
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AT sharmanamandal cytologicalevaluationofpericardialfluidsa5yearsexperienceintertiarycarecenter
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