The transcription factor BCL11A defines distinct subsets of midbrain dopaminergic neurons

The transcription factor BCL11A defines distinct subsets of midbrain dopaminergic neurons

Summary: Midbrain dopaminergic (mDA) neurons are diverse in their projection targets, effect on behavior, and susceptibility to neurodegeneration. Little is known about the molecular mechanisms establishing this diversity during development. We show that the transcription factor BCL11A is expressed...

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Bibliographic Details
Main Authors: Marianna Tolve, Ayse Ulusoy, Nikolaos Patikas, K. Ushna S. Islam, Gabriela O. Bodea, Ece Öztürk, Bianca Broske, Astrid Mentani, Antonia Wagener, Karen M.J. van Loo, Stefan Britsch, Pengtao Liu, Walid T. Khaled, Emmanouil Metzakopian, Stephan L. Baader, Donato A. Di Monte, Sandra Blaess
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Cell Reports
Subjects:
dopaminergic neurons
development
neuronal diversity
circuits
behavior
transcription factor
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472101144X

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