Cyclodextrins and Amino Acids Enhance Solubility and Tolerability of Retinoic Acid/Tretinoin: Molecular Docking, Physicochemical, Cytotoxicity, Scratch Assay, and Topical Gel Formulations Investigation

With increasing longevity globally, the search for effective and patient-friendly anti-aging solutions has been growing. Retinoic acid (Ret) is an FDA-approved anti-aging and anti-wrinkling formula, however, its poor solubility and poor tolerability hamper its use in cosmetically accepted formulatio...

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Bibliographic Details
Main Authors: Zeinab Fathalla, Mai E. Shoman, Hebatallah S. Barakat, Adel Al Fatease, Ali H. Alamri, Hamdy Abdelkader
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/16/7/853