Intradermal tests with vasomotor agents in chronic non(infectious rhinitis
The aim of this prospective study was to examine the skin reactivity to four vasomotor agents in chronic, non-infectious rhinitis patients, and to determine whether non-allergic rhinitis (NAR) patients differ from allergic rhinitis (AR) patients. Seventy four patients with NAR and 44 with AR were su...
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2002-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2002/0042-84500201037M.pdf |
| _version_ | 1811270618227671040 |
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| author | Milošević Dušanka N. Janošević Ljiljana B. Janošević Slobodanka B. |
| author_facet | Milošević Dušanka N. Janošević Ljiljana B. Janošević Slobodanka B. |
| author_sort | Milošević Dušanka N. |
| collection | DOAJ |
| description | The aim of this prospective study was to examine the skin reactivity to four vasomotor agents in chronic, non-infectious rhinitis patients, and to determine whether non-allergic rhinitis (NAR) patients differ from allergic rhinitis (AR) patients. Seventy four patients with NAR and 44 with AR were subjected to intradermal testing with papaverin (5 mg/ml), metacholine (0.02, 0.2 and 2.0 mg/ml), histamine (0.01, 0.1, 1.0 and 10.0 μg/ml) compound 48/80 (0.01, 0.1, 1.0 and 10.0 μg/ml) and saline. It was found that the frequency of pathological skin reactivity to papaverin in the patients with NAR (25/74) was significantly greater (p=5.0·10-3) then in the patients with AR (4/44). No significant inter-group difference in skin reactivity to metacholine, histamine, compound 48/80 and saline was observed. The frequency of the total pathological skin reactivity to vasomotor agents, singly and in combinations, in patients with NAR (80%) was significantly greater (p=0.03) than in patients with AR (61%). These findings suggested that the pathological skin reactivity to papaverin, metacholine, histamine and compound 48/80 was a feature of chronic, non-infectious rhinitis patients and it was more frequently associated with non-allergic than with the allergic etiology of rhinitis. |
| first_indexed | 2024-04-12T22:05:19Z |
| format | Article |
| id | doaj.art-84ea5d328a5d4f2daab64220585215a1 |
| institution | Directory Open Access Journal |
| issn | 0042-8450 |
| language | English |
| last_indexed | 2024-04-12T22:05:19Z |
| publishDate | 2002-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-84ea5d328a5d4f2daab64220585215a12022-12-22T03:14:59ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502002-01-01591374110.2298/VSP0201037MIntradermal tests with vasomotor agents in chronic non(infectious rhinitisMilošević Dušanka N.Janošević Ljiljana B.Janošević Slobodanka B.The aim of this prospective study was to examine the skin reactivity to four vasomotor agents in chronic, non-infectious rhinitis patients, and to determine whether non-allergic rhinitis (NAR) patients differ from allergic rhinitis (AR) patients. Seventy four patients with NAR and 44 with AR were subjected to intradermal testing with papaverin (5 mg/ml), metacholine (0.02, 0.2 and 2.0 mg/ml), histamine (0.01, 0.1, 1.0 and 10.0 μg/ml) compound 48/80 (0.01, 0.1, 1.0 and 10.0 μg/ml) and saline. It was found that the frequency of pathological skin reactivity to papaverin in the patients with NAR (25/74) was significantly greater (p=5.0·10-3) then in the patients with AR (4/44). No significant inter-group difference in skin reactivity to metacholine, histamine, compound 48/80 and saline was observed. The frequency of the total pathological skin reactivity to vasomotor agents, singly and in combinations, in patients with NAR (80%) was significantly greater (p=0.03) than in patients with AR (61%). These findings suggested that the pathological skin reactivity to papaverin, metacholine, histamine and compound 48/80 was a feature of chronic, non-infectious rhinitis patients and it was more frequently associated with non-allergic than with the allergic etiology of rhinitis.http://www.doiserbia.nb.rs/img/doi/0042-8450/2002/0042-84500201037M.pdfrhinitisintradermal testsvasoconstrictor agentsvasodilator agentshistaminepapaverinmetacholine chloridep(metoxy(N(methylphenethylamin |
| spellingShingle | Milošević Dušanka N. Janošević Ljiljana B. Janošević Slobodanka B. Intradermal tests with vasomotor agents in chronic non(infectious rhinitis Vojnosanitetski Pregled rhinitis intradermal tests vasoconstrictor agents vasodilator agents histamine papaverin metacholine chloride p(metoxy(N(methylphenethylamin |
| title | Intradermal tests with vasomotor agents in chronic non(infectious rhinitis |
| title_full | Intradermal tests with vasomotor agents in chronic non(infectious rhinitis |
| title_fullStr | Intradermal tests with vasomotor agents in chronic non(infectious rhinitis |
| title_full_unstemmed | Intradermal tests with vasomotor agents in chronic non(infectious rhinitis |
| title_short | Intradermal tests with vasomotor agents in chronic non(infectious rhinitis |
| title_sort | intradermal tests with vasomotor agents in chronic non infectious rhinitis |
| topic | rhinitis intradermal tests vasoconstrictor agents vasodilator agents histamine papaverin metacholine chloride p(metoxy(N(methylphenethylamin |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2002/0042-84500201037M.pdf |
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