Treatment Adherence and Incidence of Coronary Heart Disease in Type 2 Diabetes Mellitus Patients
Previous studies showed that uncontrolled blood sugar and long-term use of several types of antidiabetic could increase the risk of coronary heart disease (CHD). This study aimed to compare the incidence of CHD in type 2 diabetes mellitus (T2DM) patients showing treatment adherence and non-adherence...
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| Format: | Article |
| Language: | English |
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Universitas Indonesia
2022-05-01
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| Series: | Kesmas: Jurnal Kesehatan Masyarakat Nasional |
| Subjects: | |
| Online Access: | https://journal.fkm.ui.ac.id/kesmas/article/view/5453 |
| _version_ | 1797696133781258240 |
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| author | Ahmad Sahlan Baniu Rani Sauriasari Woro Riyadina Pradana Soewondo |
| author_facet | Ahmad Sahlan Baniu Rani Sauriasari Woro Riyadina Pradana Soewondo |
| author_sort | Ahmad Sahlan Baniu |
| collection | DOAJ |
| description | Previous studies showed that uncontrolled blood sugar and long-term use of several types of antidiabetic could increase the risk of coronary heart disease (CHD). This study aimed to compare the incidence of CHD in type 2 diabetes mellitus (T2DM) patients showing treatment adherence and non-adherence behavior over four years. This was a retrospective cohort study with data sets obtained from the Bogor Cohort Study of Non-Communicable Disease Risk Factors. All study subjects were not diagnosed with CHD at the beginning of the study. The sample was divided into two groups; one had adhered to treatment from health centers and followed the treatment instructions (adherent group), while the other had not followed the treatment instructions (non-adherent group). Of 5,690 subjects, 276 were eligible for this study (84 in the adherent and 192 in the non-adherent group). The incidence of CHD in the non-adherent group was 2.3% higher than in the adherent group (p-value = 0.564) and had a 1.7 times greater risk of developing CHD, but not statistically significant (adjusted HR = 1.739; 95% CI = 0.673-4.490). The non-adherent T2DM patients had a greater risk of developing CHD than adherent T2DM patients. |
| first_indexed | 2024-03-12T03:21:08Z |
| format | Article |
| id | doaj.art-84eb46cb9e9f44fab3b58e86f6019682 |
| institution | Directory Open Access Journal |
| issn | 1907-7505 2460-0601 |
| language | English |
| last_indexed | 2024-03-12T03:21:08Z |
| publishDate | 2022-05-01 |
| publisher | Universitas Indonesia |
| record_format | Article |
| series | Kesmas: Jurnal Kesehatan Masyarakat Nasional |
| spelling | doaj.art-84eb46cb9e9f44fab3b58e86f60196822023-09-03T13:57:45ZengUniversitas IndonesiaKesmas: Jurnal Kesehatan Masyarakat Nasional1907-75052460-06012022-05-0117210.21109/kesmas.v17i2.54531286Treatment Adherence and Incidence of Coronary Heart Disease in Type 2 Diabetes Mellitus PatientsAhmad Sahlan Baniu0Rani Sauriasari1Woro Riyadina2Pradana Soewondo3Faculty of Pharmacy, Universitas Indonesia, Depok, IndonesiaFaculty of Pharmacy, Universitas Indonesia, Depok, IndonesiaNational Institute of Health Research and Development, Ministry of Health of the Republic of Indonesia, Jakarta, IndonesiaDivision of Endocrinology, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, IndonesiaPrevious studies showed that uncontrolled blood sugar and long-term use of several types of antidiabetic could increase the risk of coronary heart disease (CHD). This study aimed to compare the incidence of CHD in type 2 diabetes mellitus (T2DM) patients showing treatment adherence and non-adherence behavior over four years. This was a retrospective cohort study with data sets obtained from the Bogor Cohort Study of Non-Communicable Disease Risk Factors. All study subjects were not diagnosed with CHD at the beginning of the study. The sample was divided into two groups; one had adhered to treatment from health centers and followed the treatment instructions (adherent group), while the other had not followed the treatment instructions (non-adherent group). Of 5,690 subjects, 276 were eligible for this study (84 in the adherent and 192 in the non-adherent group). The incidence of CHD in the non-adherent group was 2.3% higher than in the adherent group (p-value = 0.564) and had a 1.7 times greater risk of developing CHD, but not statistically significant (adjusted HR = 1.739; 95% CI = 0.673-4.490). The non-adherent T2DM patients had a greater risk of developing CHD than adherent T2DM patients.https://journal.fkm.ui.ac.id/kesmas/article/view/5453coronary heart disease, diabetes mellitus, treatment adherence |
| spellingShingle | Ahmad Sahlan Baniu Rani Sauriasari Woro Riyadina Pradana Soewondo Treatment Adherence and Incidence of Coronary Heart Disease in Type 2 Diabetes Mellitus Patients Kesmas: Jurnal Kesehatan Masyarakat Nasional coronary heart disease, diabetes mellitus, treatment adherence |
| title | Treatment Adherence and Incidence of Coronary Heart Disease in Type 2 Diabetes Mellitus Patients |
| title_full | Treatment Adherence and Incidence of Coronary Heart Disease in Type 2 Diabetes Mellitus Patients |
| title_fullStr | Treatment Adherence and Incidence of Coronary Heart Disease in Type 2 Diabetes Mellitus Patients |
| title_full_unstemmed | Treatment Adherence and Incidence of Coronary Heart Disease in Type 2 Diabetes Mellitus Patients |
| title_short | Treatment Adherence and Incidence of Coronary Heart Disease in Type 2 Diabetes Mellitus Patients |
| title_sort | treatment adherence and incidence of coronary heart disease in type 2 diabetes mellitus patients |
| topic | coronary heart disease, diabetes mellitus, treatment adherence |
| url | https://journal.fkm.ui.ac.id/kesmas/article/view/5453 |
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