Epidemiology of Barrett's esophagus and esophageal adenocarcinoma in Spain: a unicentric study
Background: Barrett's esophagus (BE) is an acquired disease defined by the presence of intestinal metaplasia with goblet cells in the distal esophagus. The prevalence of BE has increased dramatically over the last years. Aims: The primary aims of the study were to analyze the characteristics of...
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Aran Ediciones
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| Series: | Revista Espanola de Enfermedades Digestivas |
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| author | Quetzalihuitl Arroyo-Martínez Manuel Rodríguez-Téllez Antonio García-Escudero Javier Brugal-Medina Ricardo González-Cámpora Ángel Caunedo-Álvarez |
| author_facet | Quetzalihuitl Arroyo-Martínez Manuel Rodríguez-Téllez Antonio García-Escudero Javier Brugal-Medina Ricardo González-Cámpora Ángel Caunedo-Álvarez |
| author_sort | Quetzalihuitl Arroyo-Martínez |
| collection | DOAJ |
| description | Background: Barrett's esophagus (BE) is an acquired disease defined by the presence of intestinal metaplasia with goblet cells in the distal esophagus. The prevalence of BE has increased dramatically over the last years. Aims: The primary aims of the study were to analyze the characteristics of BE and esophageal adenocarcinoma (EAC) in a Spanish health district during a follow-up period. Methodology: Sociodemographic factors, alcohol consumption and cigarette smoking were analyzed. We also studied the histological behavior and cause of death in each group. Results: In the present study 430 patients were included, 338 with BE and 92 with EAC. Incidence rates have risen from 2.25 and 1.25 per 100,000 inhabitants in 1996 to 6.5 and 4.75 per 100,000 in 2011, respectively. In the EAC group, male gender, age and alcohol consumption were higher in comparison to the BE group, and the overall survival was 23 months. In the BE group, the main causes of death were non-esophageal cancer and cardiovascular disease. Conclusions: The incidence and prevalence rates of AEC and BE have risen over the past years. Risk factors for these conditions were male gender, age and alcohol consumption. Long BE (> 3 cm) is involved in dysplasia progression. AEC diagnosis mainly occurs after neoplasia is detected and, in a few cases, due to a previous BE. Cardiovascular diseases and non-esophageal cancers have been found to be the main cause of death in BE patients. |
| first_indexed | 2024-04-13T13:37:09Z |
| format | Article |
| id | doaj.art-84f5b27e0c3d43eca019773b0bfa4a44 |
| institution | Directory Open Access Journal |
| issn | 1130-0108 |
| language | English |
| last_indexed | 2024-04-13T13:37:09Z |
| publisher | Aran Ediciones |
| record_format | Article |
| series | Revista Espanola de Enfermedades Digestivas |
| spelling | doaj.art-84f5b27e0c3d43eca019773b0bfa4a442022-12-22T02:44:46ZengAran EdicionesRevista Espanola de Enfermedades Digestivas1130-01081081060961710.17235/reed.2016.4229/2016S1130-01082016001000002Epidemiology of Barrett's esophagus and esophageal adenocarcinoma in Spain: a unicentric studyQuetzalihuitl Arroyo-Martínez0Manuel Rodríguez-Téllez1Antonio García-Escudero2Javier Brugal-Medina3Ricardo González-Cámpora4Ángel Caunedo-Álvarez5Hospitales Universitarios Virgen Macarena-Virgen del RocíoHospitales Universitarios Virgen Macarena-Virgen del RocíoHospitales Universitarios Virgen MacarenaHospitales Universitarios Virgen MacarenaHospitales Universitarios Virgen MacarenaHospitales Universitarios Virgen Macarena-Virgen del RocíoBackground: Barrett's esophagus (BE) is an acquired disease defined by the presence of intestinal metaplasia with goblet cells in the distal esophagus. The prevalence of BE has increased dramatically over the last years. Aims: The primary aims of the study were to analyze the characteristics of BE and esophageal adenocarcinoma (EAC) in a Spanish health district during a follow-up period. Methodology: Sociodemographic factors, alcohol consumption and cigarette smoking were analyzed. We also studied the histological behavior and cause of death in each group. Results: In the present study 430 patients were included, 338 with BE and 92 with EAC. Incidence rates have risen from 2.25 and 1.25 per 100,000 inhabitants in 1996 to 6.5 and 4.75 per 100,000 in 2011, respectively. In the EAC group, male gender, age and alcohol consumption were higher in comparison to the BE group, and the overall survival was 23 months. In the BE group, the main causes of death were non-esophageal cancer and cardiovascular disease. Conclusions: The incidence and prevalence rates of AEC and BE have risen over the past years. Risk factors for these conditions were male gender, age and alcohol consumption. Long BE (> 3 cm) is involved in dysplasia progression. AEC diagnosis mainly occurs after neoplasia is detected and, in a few cases, due to a previous BE. Cardiovascular diseases and non-esophageal cancers have been found to be the main cause of death in BE patients.http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082016001000002&lng=en&tlng=enAdenocarcinoma esofágicoEsófago de BarrettMetaplasiaDisplasia |
| spellingShingle | Quetzalihuitl Arroyo-Martínez Manuel Rodríguez-Téllez Antonio García-Escudero Javier Brugal-Medina Ricardo González-Cámpora Ángel Caunedo-Álvarez Epidemiology of Barrett's esophagus and esophageal adenocarcinoma in Spain: a unicentric study Revista Espanola de Enfermedades Digestivas Adenocarcinoma esofágico Esófago de Barrett Metaplasia Displasia |
| title | Epidemiology of Barrett's esophagus and esophageal adenocarcinoma in Spain: a unicentric study |
| title_full | Epidemiology of Barrett's esophagus and esophageal adenocarcinoma in Spain: a unicentric study |
| title_fullStr | Epidemiology of Barrett's esophagus and esophageal adenocarcinoma in Spain: a unicentric study |
| title_full_unstemmed | Epidemiology of Barrett's esophagus and esophageal adenocarcinoma in Spain: a unicentric study |
| title_short | Epidemiology of Barrett's esophagus and esophageal adenocarcinoma in Spain: a unicentric study |
| title_sort | epidemiology of barrett s esophagus and esophageal adenocarcinoma in spain a unicentric study |
| topic | Adenocarcinoma esofágico Esófago de Barrett Metaplasia Displasia |
| url | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082016001000002&lng=en&tlng=en |
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